| pubmed-article:3527443 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3527443 | lifeskim:mentions | umls-concept:C0036025 | lld:lifeskim |
| pubmed-article:3527443 | lifeskim:mentions | umls-concept:C1155792 | lld:lifeskim |
| pubmed-article:3527443 | lifeskim:mentions | umls-concept:C1548602 | lld:lifeskim |
| pubmed-article:3527443 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:3527443 | pubmed:dateCreated | 1986-10-9 | lld:pubmed |
| pubmed-article:3527443 | pubmed:abstractText | We investigated the effects of double-strand breaks on meiotic recombination in yeast. A double-strand break was introduced at the MATa locus by sporulation of a MAT alpha inc/MATa diploid under inducing conditions for the HO-encoded endonuclease; 14% of the resulting tetrads had undergone 4 alpha:0a conversion. Conversion at MAT was associated with co-conversion of a closely linked marker and an increased recombination frequency for flanking markers. We also studied the sporulation products of a diploid heterozygous at the HIS4 locus for an insertion of a 100 bp fragment of MATa containing the HO endonuclease cut site. Under inducing conditions, a significant number of tetrads were formed that had undergone gene conversions in favor of the HIS4+ allele. Although double-strand breaks can initiate meiotic recombination in yeast, the data suggest that they do not normally do so. | lld:pubmed |
| pubmed-article:3527443 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3527443 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3527443 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3527443 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3527443 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3527443 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3527443 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3527443 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3527443 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3527443 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:3527443 | pubmed:issn | 0092-8674 | lld:pubmed |
| pubmed-article:3527443 | pubmed:author | pubmed-author:StahlF WFW | lld:pubmed |
| pubmed-article:3527443 | pubmed:author | pubmed-author:HirtH RHR | lld:pubmed |
| pubmed-article:3527443 | pubmed:author | pubmed-author:KolodkinA LAL | lld:pubmed |
| pubmed-article:3527443 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3527443 | pubmed:day | 29 | lld:pubmed |
| pubmed-article:3527443 | pubmed:volume | 46 | lld:pubmed |
| pubmed-article:3527443 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3527443 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3527443 | pubmed:pagination | 733-40 | lld:pubmed |
| pubmed-article:3527443 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:3527443 | pubmed:meshHeading | pubmed-meshheading:3527443-... | lld:pubmed |
| pubmed-article:3527443 | pubmed:meshHeading | pubmed-meshheading:3527443-... | lld:pubmed |
| pubmed-article:3527443 | pubmed:meshHeading | pubmed-meshheading:3527443-... | lld:pubmed |
| pubmed-article:3527443 | pubmed:meshHeading | pubmed-meshheading:3527443-... | lld:pubmed |
| pubmed-article:3527443 | pubmed:meshHeading | pubmed-meshheading:3527443-... | lld:pubmed |
| pubmed-article:3527443 | pubmed:meshHeading | pubmed-meshheading:3527443-... | lld:pubmed |
| pubmed-article:3527443 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:3527443 | pubmed:articleTitle | Double-strand breaks can initiate meiotic recombination in S. cerevisiae. | lld:pubmed |
| pubmed-article:3527443 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3527443 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3527443 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:3527443 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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