pubmed-article:3517185 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3517185 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:3517185 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
pubmed-article:3517185 | lifeskim:mentions | umls-concept:C0003313 | lld:lifeskim |
pubmed-article:3517185 | lifeskim:mentions | umls-concept:C0149985 | lld:lifeskim |
pubmed-article:3517185 | pubmed:issue | 6 | lld:pubmed |
pubmed-article:3517185 | pubmed:dateCreated | 1986-6-24 | lld:pubmed |
pubmed-article:3517185 | pubmed:abstractText | Studies in animal models and in the glomerulonephritis of human secondary syphilis and results from in vitro assays have suggested a role for circulating immune complexes (CICs) in human secondary syphilis. Nine adult subjects with early secondary syphilis were studied. All patients tested had CICs on C1q-binding or Raji cell assays. Proteins previously described as Treponema pallidum-specific antigens were detected by radioimmunoblot techniques in CICs from all five subjects tested. Biopsy of early cutaneous lesions revealed immunoreactants (IgG, C3, and/or C1q) in three of nine subjects and treponemal antigen in six of eight subjects tested. Histamine was injected intradermally as a trap for CICs, and biopsy of these injection sites revealed immunoreactants in four of nine subjects and treponemal antigen in five of eight subjects tested. A neutrophilic vascular reaction consistent with CIC-mediated vessel damage was seen in three of nine lesions and six of nine histamine injection sites. Normal controls did not show these changes. | lld:pubmed |
pubmed-article:3517185 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3517185 | pubmed:language | eng | lld:pubmed |
pubmed-article:3517185 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3517185 | pubmed:citationSubset | AIM | lld:pubmed |
pubmed-article:3517185 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3517185 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3517185 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3517185 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3517185 | pubmed:month | Jun | lld:pubmed |
pubmed-article:3517185 | pubmed:issn | 0022-1899 | lld:pubmed |
pubmed-article:3517185 | pubmed:author | pubmed-author:SmithE BEB | lld:pubmed |
pubmed-article:3517185 | pubmed:author | pubmed-author:BaughnR ERE | lld:pubmed |
pubmed-article:3517185 | pubmed:author | pubmed-author:CavalloTT | lld:pubmed |
pubmed-article:3517185 | pubmed:author | pubmed-author:JorizzoJ LJL | lld:pubmed |
pubmed-article:3517185 | pubmed:author | pubmed-author:SolomonA RAR | lld:pubmed |
pubmed-article:3517185 | pubmed:author | pubmed-author:McNeelyM CMC | lld:pubmed |
pubmed-article:3517185 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3517185 | pubmed:volume | 153 | lld:pubmed |
pubmed-article:3517185 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3517185 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3517185 | pubmed:pagination | 1014-22 | lld:pubmed |
pubmed-article:3517185 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
pubmed-article:3517185 | pubmed:meshHeading | pubmed-meshheading:3517185-... | lld:pubmed |
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pubmed-article:3517185 | pubmed:meshHeading | pubmed-meshheading:3517185-... | lld:pubmed |
pubmed-article:3517185 | pubmed:year | 1986 | lld:pubmed |
pubmed-article:3517185 | pubmed:articleTitle | Role of circulating immune complexes in human secondary syphilis. | lld:pubmed |
pubmed-article:3517185 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:3517185 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:3517185 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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