| pubmed-article:3493849 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3493849 | lifeskim:mentions | umls-concept:C0007600 | lld:lifeskim |
| pubmed-article:3493849 | lifeskim:mentions | umls-concept:C0005953 | lld:lifeskim |
| pubmed-article:3493849 | lifeskim:mentions | umls-concept:C0162597 | lld:lifeskim |
| pubmed-article:3493849 | lifeskim:mentions | umls-concept:C0567416 | lld:lifeskim |
| pubmed-article:3493849 | lifeskim:mentions | umls-concept:C1171362 | lld:lifeskim |
| pubmed-article:3493849 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:3493849 | lifeskim:mentions | umls-concept:C0441889 | lld:lifeskim |
| pubmed-article:3493849 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:3493849 | lifeskim:mentions | umls-concept:C1515670 | lld:lifeskim |
| pubmed-article:3493849 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:3493849 | pubmed:dateCreated | 1987-5-1 | lld:pubmed |
| pubmed-article:3493849 | pubmed:abstractText | Bone marrow stromal cell lines have been isolated that directly support B lymphopoiesis in vitro. Single B-lineage precursors proliferate and differentiate on certain of these stromal cell lines to establish long-term B-lineage cultures. These lymphopoietic stromal cells produce novel soluble factors that support proliferation of in vitro established pre-B cell populations. Lymphoid populations established on lymphopoietic stromal cell lines lack surface Ig-bearing cells, but give rise to surface Ig+ cells when transferred to mixed bone marrow feeder layers. Several stromal lines expressed a B-lineage neoplasia marker detected by the monoclonal antibody MAb6C3. Remarkably, only the 6C3Aghi stromal lines supported long-term proliferation of B-lineage cells. We propose that the 6C3 antigen-bearing molecule may play a role in stromal cell-dependent, pre-B cell proliferation, as well as in neoplastic proliferation of pre-B leukemias. | lld:pubmed |
| pubmed-article:3493849 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3493849 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3493849 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3493849 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3493849 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3493849 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3493849 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3493849 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:3493849 | pubmed:issn | 0092-8674 | lld:pubmed |
| pubmed-article:3493849 | pubmed:author | pubmed-author:WeissmanI LIL | lld:pubmed |
| pubmed-article:3493849 | pubmed:author | pubmed-author:WhitlockC ACA | lld:pubmed |
| pubmed-article:3493849 | pubmed:author | pubmed-author:TidmarshG FGF | lld:pubmed |
| pubmed-article:3493849 | pubmed:author | pubmed-author:Muller-Siebur... | lld:pubmed |
| pubmed-article:3493849 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3493849 | pubmed:day | 27 | lld:pubmed |
| pubmed-article:3493849 | pubmed:volume | 48 | lld:pubmed |
| pubmed-article:3493849 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3493849 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3493849 | pubmed:pagination | 1009-21 | lld:pubmed |
| pubmed-article:3493849 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:3493849 | pubmed:meshHeading | pubmed-meshheading:3493849-... | lld:pubmed |
| pubmed-article:3493849 | pubmed:meshHeading | pubmed-meshheading:3493849-... | lld:pubmed |
| pubmed-article:3493849 | pubmed:meshHeading | pubmed-meshheading:3493849-... | lld:pubmed |
| pubmed-article:3493849 | pubmed:meshHeading | pubmed-meshheading:3493849-... | lld:pubmed |
| pubmed-article:3493849 | pubmed:meshHeading | pubmed-meshheading:3493849-... | lld:pubmed |
| pubmed-article:3493849 | pubmed:meshHeading | pubmed-meshheading:3493849-... | lld:pubmed |
| pubmed-article:3493849 | pubmed:meshHeading | pubmed-meshheading:3493849-... | lld:pubmed |
| pubmed-article:3493849 | pubmed:meshHeading | pubmed-meshheading:3493849-... | lld:pubmed |
| pubmed-article:3493849 | pubmed:meshHeading | pubmed-meshheading:3493849-... | lld:pubmed |
| pubmed-article:3493849 | pubmed:meshHeading | pubmed-meshheading:3493849-... | lld:pubmed |
| pubmed-article:3493849 | pubmed:meshHeading | pubmed-meshheading:3493849-... | lld:pubmed |
| pubmed-article:3493849 | pubmed:meshHeading | pubmed-meshheading:3493849-... | lld:pubmed |
| pubmed-article:3493849 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:3493849 | pubmed:articleTitle | Bone marrow stromal cell lines with lymphopoietic activity express high levels of a pre-B neoplasia-associated molecule. | lld:pubmed |
| pubmed-article:3493849 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3493849 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3493849 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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