| pubmed-article:3490968 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3490968 | lifeskim:mentions | umls-concept:C0039195 | lld:lifeskim |
| pubmed-article:3490968 | lifeskim:mentions | umls-concept:C0441635 | lld:lifeskim |
| pubmed-article:3490968 | lifeskim:mentions | umls-concept:C1522642 | lld:lifeskim |
| pubmed-article:3490968 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:3490968 | lifeskim:mentions | umls-concept:C0524889 | lld:lifeskim |
| pubmed-article:3490968 | lifeskim:mentions | umls-concept:C1511695 | lld:lifeskim |
| pubmed-article:3490968 | lifeskim:mentions | umls-concept:C0439828 | lld:lifeskim |
| pubmed-article:3490968 | lifeskim:mentions | umls-concept:C1880371 | lld:lifeskim |
| pubmed-article:3490968 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:3490968 | pubmed:dateCreated | 1986-12-19 | lld:pubmed |
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| pubmed-article:3490968 | pubmed:abstractText | Both cDNA and genomic clones of the T cell receptor (TCR) alpha- and beta-chain genes of the alloreactive cytotoxic T lymphocyte (CTL) clone F3 were examined. Two distinct rearrangement events, one functional and one non-functional, were found for both the alpha and beta loci. Thus only a single functional TCR alpha beta heterodimer could be defined, consistent with allelic exclusion in the TCR genes. The V alpha gene employed by F3 is part of a six-member V alpha subfamily. Genomic clones containing each member of this subfamily were isolated and the V alpha nucleotide sequences determined. Five of these six genes are functional; these genes differ from each other by 7-14% at the amino acid level. A single dominant hypervariable region was defined within this subfamily, in contrast to the pattern of variability seen between V alpha genes in general. | lld:pubmed |
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| pubmed-article:3490968 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3490968 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3490968 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3490968 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3490968 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:3490968 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3490968 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:3490968 | pubmed:issn | 0261-4189 | lld:pubmed |
| pubmed-article:3490968 | pubmed:author | pubmed-author:BrooksC GCG | lld:pubmed |
| pubmed-article:3490968 | pubmed:author | pubmed-author:RussellJ HJH | lld:pubmed |
| pubmed-article:3490968 | pubmed:author | pubmed-author:LohD YDY | lld:pubmed |
| pubmed-article:3490968 | pubmed:author | pubmed-author:BehlkeM AMA | lld:pubmed |
| pubmed-article:3490968 | pubmed:author | pubmed-author:ChouH SHS | lld:pubmed |
| pubmed-article:3490968 | pubmed:author | pubmed-author:GodambeS ASA | lld:pubmed |
| pubmed-article:3490968 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3490968 | pubmed:volume | 5 | lld:pubmed |
| pubmed-article:3490968 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3490968 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3490968 | pubmed:pagination | 2149-55 | lld:pubmed |
| pubmed-article:3490968 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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