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pubmed-article:3416332pubmed:abstractTextThis report presented our experience in the treatment of sinoatrial (S-A) conduction disturbances with corticosteroids. Three patients with intermittent second-degree S-A block who failed to respond to atropine and isoproterenol were treated with prednisone for 6-17 weeks. Sustained improvement in S-A conduction following prednisone administration was confirmed by repeated Holter monitoring on and off therapy. Two patients eventually regained permanent sinus rhythm, while therapy led to marked diminution in S-A block in the 3rd patient. The possible mechanisms by which steroids may improve S-A conduction are discussed. Our observation is based on a small case series, each patient serving as his own control, and as such constitutes an indication for further confirmatory studies.lld:pubmed
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pubmed-article:3416332pubmed:authorpubmed-author:AbinaderE GEGlld:pubmed
pubmed-article:3416332pubmed:authorpubmed-author:OliverEElld:pubmed
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pubmed-article:3416332pubmed:dateRevised2004-11-17lld:pubmed
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pubmed-article:3416332pubmed:year1988lld:pubmed
pubmed-article:3416332pubmed:articleTitleCorticosteroids in the management of sinoatrial block.lld:pubmed
pubmed-article:3416332pubmed:affiliationHeart Institute, Haifa Medical Center (Rothschild), Faculty of Medicine, Technion, Israel.lld:pubmed
pubmed-article:3416332pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:3416332pubmed:publicationTypeCase Reportslld:pubmed