| pubmed-article:3407609 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3407609 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:3407609 | lifeskim:mentions | umls-concept:C0053396 | lld:lifeskim |
| pubmed-article:3407609 | lifeskim:mentions | umls-concept:C0005508 | lld:lifeskim |
| pubmed-article:3407609 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:3407609 | pubmed:dateCreated | 1988-9-9 | lld:pubmed |
| pubmed-article:3407609 | pubmed:abstractText | Normal healthy volunteers were studied after they ingested various beta-carotene doses. Daily administration of 15 or 45 mg beta-carotene resulted in significant increase in plasma beta-carotene levels. The extent of increase and the pattern of plasma beta-carotene levels showed substantial interindividual variation. Absorption of beta-carotene was affected by dietary fat concentration. Individuals placed on a high-fat diet showed significant increases in plasma beta-carotene as compared with those placed on a low-fat diet. Pharmacological doses of beta-carotene (45 and 90 mg) were used in intermittent schedules (5-6 d intervals) without altering the steady state of beta-carotene plasma levels. Yellowing of the skin occasionally occurred during daily dosing with 45 mg beta-carotene without evidence of toxicity. The observed individual variation in bioavailability of beta-carotene raises questions regarding clinical use of this micronutrient. It appears that determination of target plasma beta-carotene concentrations is essential for effective use of this compound in prevention or treatment. | lld:pubmed |
| pubmed-article:3407609 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3407609 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3407609 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3407609 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:3407609 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3407609 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3407609 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3407609 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3407609 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3407609 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:3407609 | pubmed:issn | 0002-9165 | lld:pubmed |
| pubmed-article:3407609 | pubmed:author | pubmed-author:MeyerCC | lld:pubmed |
| pubmed-article:3407609 | pubmed:author | pubmed-author:FinkGG | lld:pubmed |
| pubmed-article:3407609 | pubmed:author | pubmed-author:BooneCC | lld:pubmed |
| pubmed-article:3407609 | pubmed:author | pubmed-author:MichelakisAA | lld:pubmed |
| pubmed-article:3407609 | pubmed:author | pubmed-author:DimitrovN VNV | lld:pubmed |
| pubmed-article:3407609 | pubmed:author | pubmed-author:UllreyD EDE | lld:pubmed |
| pubmed-article:3407609 | pubmed:author | pubmed-author:MaloneWW | lld:pubmed |
| pubmed-article:3407609 | pubmed:author | pubmed-author:ChenowethWW | lld:pubmed |
| pubmed-article:3407609 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3407609 | pubmed:volume | 48 | lld:pubmed |
| pubmed-article:3407609 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3407609 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3407609 | pubmed:pagination | 298-304 | lld:pubmed |
| pubmed-article:3407609 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:3407609 | pubmed:meshHeading | pubmed-meshheading:3407609-... | lld:pubmed |
| pubmed-article:3407609 | pubmed:meshHeading | pubmed-meshheading:3407609-... | lld:pubmed |
| pubmed-article:3407609 | pubmed:meshHeading | pubmed-meshheading:3407609-... | lld:pubmed |
| pubmed-article:3407609 | pubmed:meshHeading | pubmed-meshheading:3407609-... | lld:pubmed |
| pubmed-article:3407609 | pubmed:meshHeading | pubmed-meshheading:3407609-... | lld:pubmed |
| pubmed-article:3407609 | pubmed:meshHeading | pubmed-meshheading:3407609-... | lld:pubmed |
| pubmed-article:3407609 | pubmed:meshHeading | pubmed-meshheading:3407609-... | lld:pubmed |
| pubmed-article:3407609 | pubmed:meshHeading | pubmed-meshheading:3407609-... | lld:pubmed |
| pubmed-article:3407609 | pubmed:meshHeading | pubmed-meshheading:3407609-... | lld:pubmed |
| pubmed-article:3407609 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3407609 | pubmed:articleTitle | Bioavailability of beta-carotene in humans. | lld:pubmed |
| pubmed-article:3407609 | pubmed:affiliation | Department of Medicine, Michigan State University, East Lansing. | lld:pubmed |
| pubmed-article:3407609 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3407609 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:3407609 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3407609 | pubmed:publicationType | Controlled Clinical Trial | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3407609 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3407609 | lld:pubmed |
