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pubmed-article:3398920pubmed:abstractTextThe CTF/NF-I group of cellular DNA binding proteins recognizes the sequence GCCAAT and is implicated in eukaryotic transcription as well as DNA replication. Molecular analysis of human CTF/NF-I complementary DNA clones reveals multiple messenger RNA species containing alternative coding regions, apparently as a result of differential splicing. Expression and functional analysis establish that individual gene products can bind to GCCAAT recognition sites and serve both as promoter-selective transcriptional activators and as initiation factors for DNA replication.lld:pubmed
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pubmed-article:3398920pubmed:articleTitleA family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs.lld:pubmed
pubmed-article:3398920pubmed:affiliationHoward Hughes Medical Institute, Department of Biochemistry, University of California, Berkeley.lld:pubmed
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