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pubmed-article:3387492pubmed:abstractTextThe effect of repeated food restriction-refeeding (weight cycling) on macronutrient selection and adiposity was investigated in female Sprague-Dawley rats. Rats were maintained on ad lib macronutrient self-selection and were put on one of two types of restriction. One group was reduced to 75% of their body weight on restricted amounts of chow and a second group was given ad lib chow during the concurrent period and were voluntarily hypophagic. During refeeding on macronutrient self-selection, animals previously restricted selected a higher percentage of dietary fat, had larger adipose depots and plasma insulin values, and had lower heart weights both expressed in grams and as a percentage of body weight than non-restricted groups. This suggests that both severe and moderate periods of restriction may have negative health consequences.lld:pubmed
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pubmed-article:3387492pubmed:year1988lld:pubmed
pubmed-article:3387492pubmed:articleTitleWeight cycling in female rats increases dietary fat selection and adiposity.lld:pubmed
pubmed-article:3387492pubmed:affiliationMonell Chemical Senses Center, Philadelphia, PA 19104.lld:pubmed
pubmed-article:3387492pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:3387492pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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