| pubmed-article:3372994 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3372994 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
| pubmed-article:3372994 | lifeskim:mentions | umls-concept:C0003250 | lld:lifeskim |
| pubmed-article:3372994 | lifeskim:mentions | umls-concept:C0021013 | lld:lifeskim |
| pubmed-article:3372994 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:3372994 | lifeskim:mentions | umls-concept:C0205214 | lld:lifeskim |
| pubmed-article:3372994 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:3372994 | pubmed:dateCreated | 1988-6-29 | lld:pubmed |
| pubmed-article:3372994 | pubmed:abstractText | In these studies we describe the production of three mAb raised to an idiotype on an IgG anticasein antibody isolated from the serum of one IgA-deficient blood donor. These are IgM kappa and block the binding of casein Ag to anticasein antibody. Sera of unrelated IgA-deficient donors were tested for the presence of the idiotype; 15 of 56 IgA-deficient sera (25%) contain the anticasein idiotype, whereas 1 of 45 normal sera was positive. Anticasein antibodies as a whole were predominantly of the IgG1 and IgG3 subclass; idiotype-positive anticaseins are predominantly of the IgG1 subclass. For IgA-deficient donors, the relative amount of idiotype-positive anticasein antibody was correlated with the level of anticasein present in the serum. Studies were done to investigate the potential inheritance of the idiotype in families; in three of four families the idiotype was inherited in an apparent autosomal dominant pattern. Our data show that a common cross-reactive idiotype can be detected in the sera of IgA-deficient individuals and their family members. This suggests that V region markers may be conserved in this humoral immunodeficiency disease. | lld:pubmed |
| pubmed-article:3372994 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3372994 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3372994 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3372994 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3372994 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:3372994 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3372994 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3372994 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3372994 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3372994 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3372994 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:3372994 | pubmed:issn | 0022-1767 | lld:pubmed |
| pubmed-article:3372994 | pubmed:author | pubmed-author:CimaGG | lld:pubmed |
| pubmed-article:3372994 | pubmed:author | pubmed-author:Cunningham-Ru... | lld:pubmed |
| pubmed-article:3372994 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3372994 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:3372994 | pubmed:volume | 140 | lld:pubmed |
| pubmed-article:3372994 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3372994 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3372994 | pubmed:pagination | 3880-6 | lld:pubmed |
| pubmed-article:3372994 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:3372994 | pubmed:meshHeading | pubmed-meshheading:3372994-... | lld:pubmed |
| pubmed-article:3372994 | pubmed:meshHeading | pubmed-meshheading:3372994-... | lld:pubmed |
| pubmed-article:3372994 | pubmed:meshHeading | pubmed-meshheading:3372994-... | lld:pubmed |
| pubmed-article:3372994 | pubmed:meshHeading | pubmed-meshheading:3372994-... | lld:pubmed |
| pubmed-article:3372994 | pubmed:meshHeading | pubmed-meshheading:3372994-... | lld:pubmed |
| pubmed-article:3372994 | pubmed:meshHeading | pubmed-meshheading:3372994-... | lld:pubmed |
| pubmed-article:3372994 | pubmed:meshHeading | pubmed-meshheading:3372994-... | lld:pubmed |
| pubmed-article:3372994 | pubmed:meshHeading | pubmed-meshheading:3372994-... | lld:pubmed |
| pubmed-article:3372994 | pubmed:meshHeading | pubmed-meshheading:3372994-... | lld:pubmed |
| pubmed-article:3372994 | pubmed:meshHeading | pubmed-meshheading:3372994-... | lld:pubmed |
| pubmed-article:3372994 | pubmed:meshHeading | pubmed-meshheading:3372994-... | lld:pubmed |
| pubmed-article:3372994 | pubmed:meshHeading | pubmed-meshheading:3372994-... | lld:pubmed |
| pubmed-article:3372994 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3372994 | pubmed:articleTitle | Analysis of a common inheritable idiotype in IgA-deficient sera using monoclonal antibodies. | lld:pubmed |
| pubmed-article:3372994 | pubmed:affiliation | Department of Medicine, Mount Sinai School of Medicine, New York 10029. | lld:pubmed |
| pubmed-article:3372994 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3372994 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3372994 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
