| pubmed-article:3367653 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3367653 | lifeskim:mentions | umls-concept:C1515841 | lld:lifeskim |
| pubmed-article:3367653 | lifeskim:mentions | umls-concept:C1336745 | lld:lifeskim |
| pubmed-article:3367653 | lifeskim:mentions | umls-concept:C1171362 | lld:lifeskim |
| pubmed-article:3367653 | lifeskim:mentions | umls-concept:C0003324 | lld:lifeskim |
| pubmed-article:3367653 | lifeskim:mentions | umls-concept:C0031437 | lld:lifeskim |
| pubmed-article:3367653 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:3367653 | lifeskim:mentions | umls-concept:C1515670 | lld:lifeskim |
| pubmed-article:3367653 | lifeskim:mentions | umls-concept:C0205359 | lld:lifeskim |
| pubmed-article:3367653 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:3367653 | pubmed:dateCreated | 1988-6-20 | lld:pubmed |
| pubmed-article:3367653 | pubmed:abstractText | Spontaneous and N-methyl-N-nitrosourea (MNU)-induced AKR/J thymic lymphomas were characterized for expression of several lymphocyte differentiation antigens. The majority (53%) of spontaneous lymphomas expressed both Lyt-2 and L3T4 antigens, similar to the predominant normal thymocyte subset. In contrast, 63% of the thymic lymphomas induced by the chemical carcinogen MNU, expressed an Lyt-2+ L3T4- antigenic profile. Although this profile suggested that MNU-induced lymphomas are phenotypically similar to a mature thymocyte subset, the presence of ThB antigen on Lyt-2+ L3T4- lymphomas did not support this notion. Diagonal gel electrophoresis of 125I-labeled membrane extracts and immunoprecipitates revealed that 17 of 29 Lyt-2+ L3T4-MNU-induced lymphomas expressed cell surface T-cell receptor heterodimer components. Northern blot analyses confirmed that the T-cell receptor material was composed of alpha and beta polypeptide chains. The results from this study indicate a distinct origin or differentiation potential of the target cells involved in viral and chemical induced lymphomagenesis of AKR/J mice. | lld:pubmed |
| pubmed-article:3367653 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3367653 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3367653 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3367653 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3367653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3367653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3367653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3367653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3367653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3367653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3367653 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3367653 | pubmed:issn | 0145-2126 | lld:pubmed |
| pubmed-article:3367653 | pubmed:author | pubmed-author:RichieE RER | lld:pubmed |
| pubmed-article:3367653 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3367653 | pubmed:volume | 12 | lld:pubmed |
| pubmed-article:3367653 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3367653 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3367653 | pubmed:pagination | 233-42 | lld:pubmed |
| pubmed-article:3367653 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:3367653 | pubmed:meshHeading | pubmed-meshheading:3367653-... | lld:pubmed |
| pubmed-article:3367653 | pubmed:meshHeading | pubmed-meshheading:3367653-... | lld:pubmed |
| pubmed-article:3367653 | pubmed:meshHeading | pubmed-meshheading:3367653-... | lld:pubmed |
| pubmed-article:3367653 | pubmed:meshHeading | pubmed-meshheading:3367653-... | lld:pubmed |
| pubmed-article:3367653 | pubmed:meshHeading | pubmed-meshheading:3367653-... | lld:pubmed |
| pubmed-article:3367653 | pubmed:meshHeading | pubmed-meshheading:3367653-... | lld:pubmed |
| pubmed-article:3367653 | pubmed:meshHeading | pubmed-meshheading:3367653-... | lld:pubmed |
| pubmed-article:3367653 | pubmed:meshHeading | pubmed-meshheading:3367653-... | lld:pubmed |
| pubmed-article:3367653 | pubmed:meshHeading | pubmed-meshheading:3367653-... | lld:pubmed |
| pubmed-article:3367653 | pubmed:meshHeading | pubmed-meshheading:3367653-... | lld:pubmed |
| pubmed-article:3367653 | pubmed:meshHeading | pubmed-meshheading:3367653-... | lld:pubmed |
| pubmed-article:3367653 | pubmed:meshHeading | pubmed-meshheading:3367653-... | lld:pubmed |
| pubmed-article:3367653 | pubmed:meshHeading | pubmed-meshheading:3367653-... | lld:pubmed |
| pubmed-article:3367653 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3367653 | pubmed:articleTitle | N-methyl-N-nitrosourea-induced and spontaneous AKR/J thymic lymphomas express distinct differentiation antigen phenotypes. | lld:pubmed |
| pubmed-article:3367653 | pubmed:affiliation | University of Texas System Cancer Center, Science Park-Research Division, Smithville 78957. | lld:pubmed |
| pubmed-article:3367653 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3367653 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3367653 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3367653 | lld:pubmed |
