| pubmed-article:3343588 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3343588 | lifeskim:mentions | umls-concept:C0001688 | lld:lifeskim |
| pubmed-article:3343588 | lifeskim:mentions | umls-concept:C0282476 | lld:lifeskim |
| pubmed-article:3343588 | lifeskim:mentions | umls-concept:C0009905 | lld:lifeskim |
| pubmed-article:3343588 | lifeskim:mentions | umls-concept:C0205487 | lld:lifeskim |
| pubmed-article:3343588 | lifeskim:mentions | umls-concept:C0879626 | lld:lifeskim |
| pubmed-article:3343588 | lifeskim:mentions | umls-concept:C1096782 | lld:lifeskim |
| pubmed-article:3343588 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:3343588 | pubmed:dateCreated | 1988-4-6 | lld:pubmed |
| pubmed-article:3343588 | pubmed:abstractText | Oral contraceptive (ORC)-related depression and irritability are among the most commonly reported drug-induced psychiatric symptoms. To investigate the etiological role of genetic factors in ORC-related symptoms, we studied questionnaire responses in 715 monozygotic and 416 dizygotic volunteer twin pairs concordant for ORC usage. Biometrical genetic analysis indicated that the liability to ORC-related depression was clearly influenced by genetic but not familial-environmental factors. Similar, but less definitive, results were found for ORC-related irritability. Multivariate genetic analysis indicated that both the genetic and the individual-specific environmental factors that influenced the liability to ORC-related depression and irritability were largely distinct from those that influence baseline levels of psychiatric symptoms. Genes play an important etiological role in ORC-related psychiatric side effects. The genes that influence liability to these side effects appear to differ from those that are etiologically important in baseline psychiatric symptomatology. | lld:pubmed |
| pubmed-article:3343588 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3343588 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3343588 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3343588 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3343588 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3343588 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:3343588 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3343588 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3343588 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:3343588 | pubmed:issn | 0022-3018 | lld:pubmed |
| pubmed-article:3343588 | pubmed:author | pubmed-author:HandelsmanDD | lld:pubmed |
| pubmed-article:3343588 | pubmed:author | pubmed-author:KendlerK SKS | lld:pubmed |
| pubmed-article:3343588 | pubmed:author | pubmed-author:EavesL JLJ | lld:pubmed |
| pubmed-article:3343588 | pubmed:author | pubmed-author:MartinN GNG | lld:pubmed |
| pubmed-article:3343588 | pubmed:author | pubmed-author:HeathA CAC | lld:pubmed |
| pubmed-article:3343588 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3343588 | pubmed:volume | 176 | lld:pubmed |
| pubmed-article:3343588 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3343588 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3343588 | pubmed:pagination | 153-60 | lld:pubmed |
| pubmed-article:3343588 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:3343588 | pubmed:meshHeading | pubmed-meshheading:3343588-... | lld:pubmed |
| pubmed-article:3343588 | pubmed:meshHeading | pubmed-meshheading:3343588-... | lld:pubmed |
| pubmed-article:3343588 | pubmed:meshHeading | pubmed-meshheading:3343588-... | lld:pubmed |
| pubmed-article:3343588 | pubmed:meshHeading | pubmed-meshheading:3343588-... | lld:pubmed |
| pubmed-article:3343588 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3343588 | pubmed:articleTitle | A twin study of the psychiatric side effects of oral contraceptives. | lld:pubmed |
| pubmed-article:3343588 | pubmed:affiliation | Department of Human Genetics, Medical College of Virginia/Virginia Commonwealth University, Richmond 23298. | lld:pubmed |
| pubmed-article:3343588 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3343588 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3343588 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3343588 | lld:pubmed |
