| pubmed-article:3258549 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3258549 | lifeskim:mentions | umls-concept:C0029246 | lld:lifeskim |
| pubmed-article:3258549 | lifeskim:mentions | umls-concept:C1706515 | lld:lifeskim |
| pubmed-article:3258549 | lifeskim:mentions | umls-concept:C0024264 | lld:lifeskim |
| pubmed-article:3258549 | lifeskim:mentions | umls-concept:C0007603 | lld:lifeskim |
| pubmed-article:3258549 | lifeskim:mentions | umls-concept:C0007589 | lld:lifeskim |
| pubmed-article:3258549 | lifeskim:mentions | umls-concept:C1704640 | lld:lifeskim |
| pubmed-article:3258549 | lifeskim:mentions | umls-concept:C1704675 | lld:lifeskim |
| pubmed-article:3258549 | lifeskim:mentions | umls-concept:C0205148 | lld:lifeskim |
| pubmed-article:3258549 | lifeskim:mentions | umls-concept:C1306673 | lld:lifeskim |
| pubmed-article:3258549 | lifeskim:mentions | umls-concept:C1553412 | lld:lifeskim |
| pubmed-article:3258549 | lifeskim:mentions | umls-concept:C1548328 | lld:lifeskim |
| pubmed-article:3258549 | lifeskim:mentions | umls-concept:C1511938 | lld:lifeskim |
| pubmed-article:3258549 | lifeskim:mentions | umls-concept:C0331858 | lld:lifeskim |
| pubmed-article:3258549 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:3258549 | pubmed:dateCreated | 1988-5-24 | lld:pubmed |
| pubmed-article:3258549 | pubmed:abstractText | Composition of surface proteins and their interactions with cytoskeleton or membrane matrix were compared in tumor B-cell lines of different stages of B-lymphocyte maturation. All studied B-cell lines were found to share a similar set of cell surface proteins, which are tightly associated with the cytoskeleton. The increase in amount of detergent-unextractable cell surface proteins with B-cell maturation suggested that differentiation of B lymphocytes was accompanied by development of specific interactions between surface proteins and elements of the cytoskeleton or membrane matrix. Using a recently developed procedure for lymphocyte plasma membrane fractionation we demonstrate changes in distribution of cell surface proteins in membrane matrix-rich and membrane matrix-poor plasma membrane fractions during B-lymphocyte maturation. Thus, cell surface proteins of the mature B-cell line MOPC-315 were predominantly found in the plasma membrane vesicles of a high buoyant density. These vesicles mostly contained plasma membrane proteins tightly associated with elements of the membrane matrix. In immature B cells (line 70Z3) virtually all surface proteins were detected in both low and high buoyant density membrane vesicles. The tendency to increased associations between surface proteins and cytoskeleton/membrane matrix with maturation of B cells could not be explained by increased amounts of filamentous actin, since no correlation was found between the amount of globular or filamentous actin and the degree of surface protein-cytoskeleton (membrane matrix) interactions. | lld:pubmed |
| pubmed-article:3258549 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3258549 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3258549 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3258549 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3258549 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3258549 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3258549 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:3258549 | pubmed:issn | 0045-6039 | lld:pubmed |
| pubmed-article:3258549 | pubmed:author | pubmed-author:MorseH CHC3rd | lld:pubmed |
| pubmed-article:3258549 | pubmed:author | pubmed-author:TakayamaHH | lld:pubmed |
| pubmed-article:3258549 | pubmed:author | pubmed-author:DavidsonW FWF | lld:pubmed |
| pubmed-article:3258549 | pubmed:author | pubmed-author:TrentMM | lld:pubmed |
| pubmed-article:3258549 | pubmed:author | pubmed-author:SitkovskyM... | lld:pubmed |
| pubmed-article:3258549 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3258549 | pubmed:volume | 22 | lld:pubmed |
| pubmed-article:3258549 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3258549 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3258549 | pubmed:pagination | 233-44 | lld:pubmed |
| pubmed-article:3258549 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:3258549 | pubmed:meshHeading | pubmed-meshheading:3258549-... | lld:pubmed |
| pubmed-article:3258549 | pubmed:meshHeading | pubmed-meshheading:3258549-... | lld:pubmed |
| pubmed-article:3258549 | pubmed:meshHeading | pubmed-meshheading:3258549-... | lld:pubmed |
| pubmed-article:3258549 | pubmed:meshHeading | pubmed-meshheading:3258549-... | lld:pubmed |
| pubmed-article:3258549 | pubmed:meshHeading | pubmed-meshheading:3258549-... | lld:pubmed |
| pubmed-article:3258549 | pubmed:meshHeading | pubmed-meshheading:3258549-... | lld:pubmed |
| pubmed-article:3258549 | pubmed:meshHeading | pubmed-meshheading:3258549-... | lld:pubmed |
| pubmed-article:3258549 | pubmed:meshHeading | pubmed-meshheading:3258549-... | lld:pubmed |
| pubmed-article:3258549 | pubmed:meshHeading | pubmed-meshheading:3258549-... | lld:pubmed |
| pubmed-article:3258549 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3258549 | pubmed:articleTitle | Organization of lymphocyte plasma membrane. Surface protein-membrane matrix interactions in B-cell lines of different stages of differentiation. | lld:pubmed |
| pubmed-article:3258549 | pubmed:affiliation | Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892. | lld:pubmed |
| pubmed-article:3258549 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3258549 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
