pubmed-article:3147420 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3147420 | lifeskim:mentions | umls-concept:C0005149 | lld:lifeskim |
pubmed-article:3147420 | lifeskim:mentions | umls-concept:C0022702 | lld:lifeskim |
pubmed-article:3147420 | lifeskim:mentions | umls-concept:C0019014 | lld:lifeskim |
pubmed-article:3147420 | pubmed:issue | 6 | lld:pubmed |
pubmed-article:3147420 | pubmed:dateCreated | 1989-4-6 | lld:pubmed |
pubmed-article:3147420 | pubmed:abstractText | To study the kinetics of beta 2-microglobulin during haemofiltration, seven patients with end-stage renal failure were treated with the AN 69 (acrylonitrile), Duo-Flux (cellulose acetate) and F 60 (polysulphone) haemofilter. Low beta 2-microglobulin sieving coefficients and a highly negative filter mass balance error were observed during the initial phase of treatment with AN 69 but not with Duo-Flux or F 60, indicating a high degree of beta 2-microglobulin adsorption by AN 69. Total removal of beta 2-microglobulin was calculated by addition of the total amount adsorbed by the membrane and the total amount recovered in the collected ultrafiltrate. With AN 69 and F 60, total removal of beta 2-microglobulin amounted to 393 +/- 135 (SD) and 316 +/- 35 mg per treatment, while total removal with Duo-Flux was 242 +/- 79 mg per treatment. Thus, highly permeable membranes such as AN 69 or F 60 used in a haemofiltration mode may nearly balance the presumed generation of beta 2-microglobulin in uraemic patients. During treatment, an increase of the calculated beta 2-microglobulin distribution volume occurred with all three membranes, probably representing extra-to-intracellular water shifts. The water shifts occurring during haemofiltration reduce the value of precision of beta 2-microglobulin kinetics and limit the value of the plasma level decrease as an index of beta 2-microglobulin removal. | lld:pubmed |
pubmed-article:3147420 | pubmed:language | eng | lld:pubmed |
pubmed-article:3147420 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3147420 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:3147420 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:3147420 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3147420 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3147420 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3147420 | pubmed:issn | 0931-0509 | lld:pubmed |
pubmed-article:3147420 | pubmed:author | pubmed-author:ShaldonSS | lld:pubmed |
pubmed-article:3147420 | pubmed:author | pubmed-author:WilksMM | lld:pubmed |
pubmed-article:3147420 | pubmed:author | pubmed-author:KochK MKM | lld:pubmed |
pubmed-article:3147420 | pubmed:author | pubmed-author:SmebyL CLC | lld:pubmed |
pubmed-article:3147420 | pubmed:author | pubmed-author:FloegeJJ | lld:pubmed |
pubmed-article:3147420 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3147420 | pubmed:volume | 3 | lld:pubmed |
pubmed-article:3147420 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3147420 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3147420 | pubmed:pagination | 784-9 | lld:pubmed |
pubmed-article:3147420 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:3147420 | pubmed:year | 1988 | lld:pubmed |
pubmed-article:3147420 | pubmed:articleTitle | Beta 2-microglobulin kinetics during haemofiltration. | lld:pubmed |
pubmed-article:3147420 | pubmed:affiliation | Department of Nephrology, Hannover Medical School, FRG. | lld:pubmed |
pubmed-article:3147420 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:3147420 | pubmed:publicationType | Comparative Study | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3147420 | lld:pubmed |