| pubmed-article:3119271 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3119271 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:3119271 | lifeskim:mentions | umls-concept:C0348013 | lld:lifeskim |
| pubmed-article:3119271 | lifeskim:mentions | umls-concept:C0017887 | lld:lifeskim |
| pubmed-article:3119271 | lifeskim:mentions | umls-concept:C0332197 | lld:lifeskim |
| pubmed-article:3119271 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
| pubmed-article:3119271 | lifeskim:mentions | umls-concept:C0443172 | lld:lifeskim |
| pubmed-article:3119271 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:3119271 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:3119271 | pubmed:dateCreated | 1987-12-29 | lld:pubmed |
| pubmed-article:3119271 | pubmed:abstractText | We have previously demonstrated a progressive loss in the ability of the beta-receptor agonist isoproterenol to relax veins with increasing age. In this study the influence of age on the responsiveness of medium-sized veins to local infusions of nitroglycerin was studied in two groups of 15 healthy male volunteers using the dorsal hand vein compliance technique. A dorsal hand vein was preconstricted with submaximally effective doses of phenylephrine and a dose-response curve with nitroglycerin was established. The nitroglycerin dose that caused a 50% venodilation ranged from 0.7 to 22.4 ng/min (geometric mean 3.6 ng/min) in the younger group (aged 19 to 29 years; mean +/- SD 23 +/- 3 years) and from 0.2 to 17.9 ng/min (geometric mean 3.6 ng/min) in the older subjects (aged 50 to 74 years; mean +/- SD 63 +/- 7 years) (P = 0.49 between geometric means). The mean (+/- SD) maximal venodilation, based on the pretreatment baseline, was 103% +/- 65% in the younger and 125% +/- 64% in the older subjects (P = 0.18). These results indicate that there is no age-related change in venous responsiveness to nitroglycerin. | lld:pubmed |
| pubmed-article:3119271 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3119271 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3119271 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3119271 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3119271 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:3119271 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3119271 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3119271 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3119271 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:3119271 | pubmed:issn | 0009-9236 | lld:pubmed |
| pubmed-article:3119271 | pubmed:author | pubmed-author:BlaschkeT FTF | lld:pubmed |
| pubmed-article:3119271 | pubmed:author | pubmed-author:HoffmanB BBB | lld:pubmed |
| pubmed-article:3119271 | pubmed:author | pubmed-author:EichlerH GHG | lld:pubmed |
| pubmed-article:3119271 | pubmed:author | pubmed-author:KatzirDD | lld:pubmed |
| pubmed-article:3119271 | pubmed:author | pubmed-author:HiremathAA | lld:pubmed |
| pubmed-article:3119271 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3119271 | pubmed:volume | 42 | lld:pubmed |
| pubmed-article:3119271 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3119271 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3119271 | pubmed:pagination | 521-4 | lld:pubmed |
| pubmed-article:3119271 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:3119271 | pubmed:meshHeading | pubmed-meshheading:3119271-... | lld:pubmed |
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| pubmed-article:3119271 | pubmed:meshHeading | pubmed-meshheading:3119271-... | lld:pubmed |
| pubmed-article:3119271 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:3119271 | pubmed:articleTitle | Absence of age-related changes in venous responsiveness to nitroglycerin in vivo in humans. | lld:pubmed |
| pubmed-article:3119271 | pubmed:affiliation | Department of Medicine, Stanford University School of Medicine, CA. | lld:pubmed |
| pubmed-article:3119271 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3119271 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:3119271 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3119271 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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