| pubmed-article:3115300 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3115300 | lifeskim:mentions | umls-concept:C1135183 | lld:lifeskim |
| pubmed-article:3115300 | lifeskim:mentions | umls-concept:C0225336 | lld:lifeskim |
| pubmed-article:3115300 | lifeskim:mentions | umls-concept:C0003483 | lld:lifeskim |
| pubmed-article:3115300 | lifeskim:mentions | umls-concept:C0025519 | lld:lifeskim |
| pubmed-article:3115300 | lifeskim:mentions | umls-concept:C0031676 | lld:lifeskim |
| pubmed-article:3115300 | lifeskim:mentions | umls-concept:C0003695 | lld:lifeskim |
| pubmed-article:3115300 | lifeskim:mentions | umls-concept:C0031673 | lld:lifeskim |
| pubmed-article:3115300 | lifeskim:mentions | umls-concept:C0030685 | lld:lifeskim |
| pubmed-article:3115300 | lifeskim:mentions | umls-concept:C1512179 | lld:lifeskim |
| pubmed-article:3115300 | lifeskim:mentions | umls-concept:C0680255 | lld:lifeskim |
| pubmed-article:3115300 | lifeskim:mentions | umls-concept:C0391871 | lld:lifeskim |
| pubmed-article:3115300 | lifeskim:mentions | umls-concept:C1283071 | lld:lifeskim |
| pubmed-article:3115300 | lifeskim:mentions | umls-concept:C1963578 | lld:lifeskim |
| pubmed-article:3115300 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:3115300 | pubmed:dateCreated | 1987-11-5 | lld:pubmed |
| pubmed-article:3115300 | pubmed:abstractText | Confluent cultures of porcine aortic endothelial cells were prelabeled with 1 microM [14C]arachidonic acid complexed to 1 microM bovine serum albumin. After washing, the cells were stimulated with 1 microM A23187 for time intervals between 30 s and 30 min. Cellular lipids were extracted and separated into major lipid classes and phospholipid subclasses. The external medium was analyzed for released radioactive eicosanoids. The time-course of total release of 14C radioactivity demonstrated a biphasic nature of A23187-induced changes in endothelial cell lipids. Early, from 30 s to 5 min, substantial losses of [14C]arachidonic acid from diacylphosphatidylethanolamine and phosphatidylinositol, as well as an abrupt increase in diacylphosphatidylcholine-associated radioactivity were observed. These initial changes coincided with the release of 14C-labeled cyclooxygenase products. Later changes (5-30 min) included a sustained progressive loss of 14C radioactivity from alkenyl (alk-1-enyl) acylphosphatidylethanolamine and diacylphosphatidylcholine. These later changes coincided with the elaboration of 14C-labeled lipoxygenase products. Although unequivocal assignments cannot be made, the data suggest that specific pools of arachidonic acid provide precursors for individual classes of eicosanoids. | lld:pubmed |
| pubmed-article:3115300 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3115300 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3115300 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3115300 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:3115300 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3115300 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:3115300 | pubmed:issn | 0006-3002 | lld:pubmed |
| pubmed-article:3115300 | pubmed:author | pubmed-author:BrownM LML | lld:pubmed |
| pubmed-article:3115300 | pubmed:author | pubmed-author:DeykinDD | lld:pubmed |
| pubmed-article:3115300 | pubmed:author | pubmed-author:JakubowskiJ... | lld:pubmed |
| pubmed-article:3115300 | pubmed:author | pubmed-author:LeventisL LLL | lld:pubmed |
| pubmed-article:3115300 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3115300 | pubmed:day | 25 | lld:pubmed |
| pubmed-article:3115300 | pubmed:volume | 921 | lld:pubmed |
| pubmed-article:3115300 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3115300 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3115300 | pubmed:pagination | 159-66 | lld:pubmed |
| pubmed-article:3115300 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:3115300 | pubmed:meshHeading | pubmed-meshheading:3115300-... | lld:pubmed |
| pubmed-article:3115300 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:3115300 | pubmed:articleTitle | Ionophore-induced metabolism of phospholipids and eicosanoid production in porcine aortic endothelial cells: selective release of arachidonic acid from diacyl and ether phospholipids. | lld:pubmed |
| pubmed-article:3115300 | pubmed:affiliation | Department of Medicine and Biochemistry, Boston University School of Medicine, MA. | lld:pubmed |
| pubmed-article:3115300 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3115300 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3115300 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
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