pubmed-article:3105936 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3105936 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
pubmed-article:3105936 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
pubmed-article:3105936 | lifeskim:mentions | umls-concept:C0032231 | lld:lifeskim |
pubmed-article:3105936 | lifeskim:mentions | umls-concept:C0003209 | lld:lifeskim |
pubmed-article:3105936 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
pubmed-article:3105936 | lifeskim:mentions | umls-concept:C1515999 | lld:lifeskim |
pubmed-article:3105936 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:3105936 | pubmed:dateCreated | 1987-6-12 | lld:pubmed |
pubmed-article:3105936 | pubmed:abstractText | The effect of IFN-beta on the development of the inflammatory reaction was studied in an experimental animal model, carrageenan-induced pleurisy in the mouse. Intrapleural inoculation of IFN-beta at the same time as carrageenan administration inhibited both migration of inflammatory cells and exudate formation in the pleural cavity in a dose-dependent fashion. Similarly, IFN-beta decreased the presence of the arachidonate metabolites PGI2, TXA2 and PGE2 (highly active molecules involved in the regulation of the inflammatory reaction) in inflammatory exudates. A marked inhibition of the inflammatory response to carrageenan was also evident when IFN-beta was administered several hours after the inflammatory challenge. In contrast, administration of IFN-gamma did not modify significantly any of the inflammatory parameters considered. | lld:pubmed |
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pubmed-article:3105936 | pubmed:language | eng | lld:pubmed |
pubmed-article:3105936 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3105936 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:3105936 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3105936 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:3105936 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3105936 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3105936 | pubmed:month | Dec | lld:pubmed |
pubmed-article:3105936 | pubmed:issn | 0009-9104 | lld:pubmed |
pubmed-article:3105936 | pubmed:author | pubmed-author:TagliabueAA | lld:pubmed |
pubmed-article:3105936 | pubmed:author | pubmed-author:BoraschiDD | lld:pubmed |
pubmed-article:3105936 | pubmed:author | pubmed-author:GhiaraPP | lld:pubmed |
pubmed-article:3105936 | pubmed:author | pubmed-author:BartaliniMM | lld:pubmed |
pubmed-article:3105936 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3105936 | pubmed:volume | 66 | lld:pubmed |
pubmed-article:3105936 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3105936 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3105936 | pubmed:pagination | 606-14 | lld:pubmed |
pubmed-article:3105936 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:3105936 | pubmed:year | 1986 | lld:pubmed |
pubmed-article:3105936 | pubmed:articleTitle | Anti-inflammatory activity of IFN-beta in carrageenan-induced pleurisy in the mouse. | lld:pubmed |
pubmed-article:3105936 | pubmed:publicationType | Journal Article | lld:pubmed |