| pubmed-article:3105057 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3105057 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:3105057 | lifeskim:mentions | umls-concept:C0036536 | lld:lifeskim |
| pubmed-article:3105057 | lifeskim:mentions | umls-concept:C0036537 | lld:lifeskim |
| pubmed-article:3105057 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
| pubmed-article:3105057 | lifeskim:mentions | umls-concept:C0035448 | lld:lifeskim |
| pubmed-article:3105057 | pubmed:issue | 4797 | lld:pubmed |
| pubmed-article:3105057 | pubmed:dateCreated | 1987-5-7 | lld:pubmed |
| pubmed-article:3105057 | pubmed:abstractText | A human B cell subpopulation identifiable by the expression of the cell surface antigen Leu-1 (CD5) is responsible for most of the immunoglobulin M rheumatoid factor secreted in vitro after the cells are stimulated with Staphylococcus aureus. The ability of B cells bearing the Leu-1 marker (Leu-1+) to secrete rheumatoid factor is present early in development and extends to adulthood, since Leu-1+ B cells from cord blood and from peripheral blood lymphocytes of both normal adults and patients with certain autoimmune conditions secrete rheumatoid factor in comparable amounts. The neonatal enrichment of Leu-1+ B cells, the presence of Leu-1+ B cells in increased frequencies in patients with autoimmune disease, and the involvement of Leu-1+ B cells in autoantibody secretion suggest both developmental and functional homologies between this human B cell subpopulation and the murine Ly-1 B cell subpopulation. | lld:pubmed |
| pubmed-article:3105057 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3105057 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3105057 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3105057 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:3105057 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3105057 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3105057 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:3105057 | pubmed:issn | 0036-8075 | lld:pubmed |
| pubmed-article:3105057 | pubmed:author | pubmed-author:ShimizuMM | lld:pubmed |
| pubmed-article:3105057 | pubmed:author | pubmed-author:YamasakiKK | lld:pubmed |
| pubmed-article:3105057 | pubmed:author | pubmed-author:HayakawaKK | lld:pubmed |
| pubmed-article:3105057 | pubmed:author | pubmed-author:KishimotoTT | lld:pubmed |
| pubmed-article:3105057 | pubmed:author | pubmed-author:HardyR RRR | lld:pubmed |
| pubmed-article:3105057 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3105057 | pubmed:day | 3 | lld:pubmed |
| pubmed-article:3105057 | pubmed:volume | 236 | lld:pubmed |
| pubmed-article:3105057 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3105057 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3105057 | pubmed:pagination | 81-3 | lld:pubmed |
| pubmed-article:3105057 | pubmed:dateRevised | 2007-3-19 | lld:pubmed |
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| pubmed-article:3105057 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:3105057 | pubmed:articleTitle | Rheumatoid factor secretion from human Leu-1+ B cells. | lld:pubmed |
| pubmed-article:3105057 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3105057 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:3105057 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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