| pubmed-article:3070277 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3070277 | lifeskim:mentions | umls-concept:C0006644 | lld:lifeskim |
| pubmed-article:3070277 | lifeskim:mentions | umls-concept:C0012155 | lld:lifeskim |
| pubmed-article:3070277 | lifeskim:mentions | umls-concept:C0026879 | lld:lifeskim |
| pubmed-article:3070277 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:3070277 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:3070277 | pubmed:dateCreated | 1989-4-26 | lld:pubmed |
| pubmed-article:3070277 | pubmed:abstractText | Hepatic microsomal fractions (microsomes) were prepared from female BALB/c mice. The potential of caffeine to modify the ability of microsomes to convert the heterocyclic aromatic amines MeIQ, Trp-P-2 and MeIQx, to bacterial mutagens (indicator: Salmonella typhimurium TA98) was investigated. Caffeine inhibited mutagenicity and did so by inhibiting microsomal metabolism of the three compounds, rather than by altering uptake of the active mutagens and/or interacting with the DNA repair processes in the bacterial cell. Notional Ki values determined for the three heterocyclic amines were similar, suggesting that caffeine inhibits at a stage common to the metabolism of all three compounds. | lld:pubmed |
| pubmed-article:3070277 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3070277 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3070277 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3070277 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3070277 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3070277 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3070277 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:3070277 | pubmed:issn | 0267-8357 | lld:pubmed |
| pubmed-article:3070277 | pubmed:author | pubmed-author:AlldrickA JAJ | lld:pubmed |
| pubmed-article:3070277 | pubmed:author | pubmed-author:RowlandI RIR | lld:pubmed |
| pubmed-article:3070277 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3070277 | pubmed:volume | 3 | lld:pubmed |
| pubmed-article:3070277 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3070277 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3070277 | pubmed:pagination | 423-7 | lld:pubmed |
| pubmed-article:3070277 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:3070277 | pubmed:meshHeading | pubmed-meshheading:3070277-... | lld:pubmed |
| pubmed-article:3070277 | pubmed:meshHeading | pubmed-meshheading:3070277-... | lld:pubmed |
| pubmed-article:3070277 | pubmed:meshHeading | pubmed-meshheading:3070277-... | lld:pubmed |
| pubmed-article:3070277 | pubmed:meshHeading | pubmed-meshheading:3070277-... | lld:pubmed |
| pubmed-article:3070277 | pubmed:meshHeading | pubmed-meshheading:3070277-... | lld:pubmed |
| pubmed-article:3070277 | pubmed:meshHeading | pubmed-meshheading:3070277-... | lld:pubmed |
| pubmed-article:3070277 | pubmed:meshHeading | pubmed-meshheading:3070277-... | lld:pubmed |
| pubmed-article:3070277 | pubmed:meshHeading | pubmed-meshheading:3070277-... | lld:pubmed |
| pubmed-article:3070277 | pubmed:meshHeading | pubmed-meshheading:3070277-... | lld:pubmed |
| pubmed-article:3070277 | pubmed:meshHeading | pubmed-meshheading:3070277-... | lld:pubmed |
| pubmed-article:3070277 | pubmed:meshHeading | pubmed-meshheading:3070277-... | lld:pubmed |
| pubmed-article:3070277 | pubmed:meshHeading | pubmed-meshheading:3070277-... | lld:pubmed |
| pubmed-article:3070277 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3070277 | pubmed:articleTitle | Caffeine inhibits hepatic-microsomal activation of some dietary genotoxins. | lld:pubmed |
| pubmed-article:3070277 | pubmed:affiliation | Department of Microbiology, British Industrial Biological Research Association, Carshalton, Surrey, UK. | lld:pubmed |
| pubmed-article:3070277 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3070277 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
