pubmed-article:3024496 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3024496 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
pubmed-article:3024496 | lifeskim:mentions | umls-concept:C0086045 | lld:lifeskim |
pubmed-article:3024496 | lifeskim:mentions | umls-concept:C0005528 | lld:lifeskim |
pubmed-article:3024496 | lifeskim:mentions | umls-concept:C0017725 | lld:lifeskim |
pubmed-article:3024496 | pubmed:issue | 6 Pt 1 | lld:pubmed |
pubmed-article:3024496 | pubmed:dateCreated | 1987-1-20 | lld:pubmed |
pubmed-article:3024496 | pubmed:abstractText | The uptake of D-[U-14C]glucose and D-[5-3H]glucose by tumoral insulin-producing cells of the RINm5F line was measured over 3-30 min of incubation at 7-37 degrees C. The apparent distribution space of the hexose ranged from values as low as the L-[1-14C]glucose space to values 10 times higher than the 3H2O space. Although a major fraction of the radioactivity recovered in the cellular pellet corresponded to the metabolites of D-glucose, the results suggested that the transport of D-glucose into the tumoral cells represents a saturable and temperature-dependent process. When D-glucose was measured by an enzymic procedure in cells incubated for 30 min at 37 degrees C in the presence of 50.0 mM D-glucose, the apparent distribution space of the hexose remained lower than the intracellular water space. These results indicate that the RINm5F cells have lost an essential attribute of the glucose-sensing device in normal insulin-producing cells, namely the ability to ensure the equilibration of D-glucose concentrations across the plasma membrane. | lld:pubmed |
pubmed-article:3024496 | pubmed:language | eng | lld:pubmed |
pubmed-article:3024496 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3024496 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:3024496 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3024496 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3024496 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3024496 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3024496 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3024496 | pubmed:month | Dec | lld:pubmed |
pubmed-article:3024496 | pubmed:issn | 0002-9513 | lld:pubmed |
pubmed-article:3024496 | pubmed:author | pubmed-author:MalaisseW JWJ | lld:pubmed |
pubmed-article:3024496 | pubmed:author | pubmed-author:SenerAA | lld:pubmed |
pubmed-article:3024496 | pubmed:author | pubmed-author:GiroixM HMH | lld:pubmed |
pubmed-article:3024496 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3024496 | pubmed:volume | 251 | lld:pubmed |
pubmed-article:3024496 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3024496 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3024496 | pubmed:pagination | C847-51 | lld:pubmed |
pubmed-article:3024496 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:3024496 | pubmed:meshHeading | pubmed-meshheading:3024496-... | lld:pubmed |
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pubmed-article:3024496 | pubmed:year | 1986 | lld:pubmed |
pubmed-article:3024496 | pubmed:articleTitle | D-glucose transport and concentration in tumoral insulin-producing cells. | lld:pubmed |
pubmed-article:3024496 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:3024496 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3024496 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3024496 | lld:pubmed |