| pubmed-article:2984806 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2984806 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:2984806 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:2984806 | lifeskim:mentions | umls-concept:C0001613 | lld:lifeskim |
| pubmed-article:2984806 | lifeskim:mentions | umls-concept:C0001617 | lld:lifeskim |
| pubmed-article:2984806 | lifeskim:mentions | umls-concept:C0040521 | lld:lifeskim |
| pubmed-article:2984806 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:2984806 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:2984806 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:2984806 | pubmed:issue | 2-3 | lld:pubmed |
| pubmed-article:2984806 | pubmed:dateCreated | 1985-4-26 | lld:pubmed |
| pubmed-article:2984806 | pubmed:abstractText | Uptake and distribution of [14C]toxaphene was studied in the adrenals of rats using whole-body autoradiography. An accumulation of radioactivity was seen in the adrenal cortex (zona fasciculata) 1-24 h after a single gavage of [14C]toxaphene (16 mg/kg b.w.). In in vitro studies toxaphene was found to inhibit ACTH-stimulated corticosterone synthesis in the cultured rat adrenocortical cells (IC50 2.8 X 10(-5) M). Moderate but significant inhibition (P less than 0.001) of ACTH-stimulated corticosterone synthesis was also observed in the adrenocortical cells isolated from rats after a prolonged exposure (5 weeks) to low levels (1.2 ppm) of toxaphene in feed. The results indicate a direct adrenotoxic effect of toxaphene. | lld:pubmed |
| pubmed-article:2984806 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2984806 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2984806 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2984806 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2984806 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2984806 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2984806 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2984806 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2984806 | pubmed:issn | 0378-4274 | lld:pubmed |
| pubmed-article:2984806 | pubmed:author | pubmed-author:RydströmJJ | lld:pubmed |
| pubmed-article:2984806 | pubmed:author | pubmed-author:SlaninaPP | lld:pubmed |
| pubmed-article:2984806 | pubmed:author | pubmed-author:MohammedAA | lld:pubmed |
| pubmed-article:2984806 | pubmed:author | pubmed-author:HallbergEE | lld:pubmed |
| pubmed-article:2984806 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2984806 | pubmed:volume | 24 | lld:pubmed |
| pubmed-article:2984806 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2984806 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2984806 | pubmed:pagination | 137-43 | lld:pubmed |
| pubmed-article:2984806 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2984806 | pubmed:meshHeading | pubmed-meshheading:2984806-... | lld:pubmed |
| pubmed-article:2984806 | pubmed:meshHeading | pubmed-meshheading:2984806-... | lld:pubmed |
| pubmed-article:2984806 | pubmed:meshHeading | pubmed-meshheading:2984806-... | lld:pubmed |
| pubmed-article:2984806 | pubmed:meshHeading | pubmed-meshheading:2984806-... | lld:pubmed |
| pubmed-article:2984806 | pubmed:meshHeading | pubmed-meshheading:2984806-... | lld:pubmed |
| pubmed-article:2984806 | pubmed:meshHeading | pubmed-meshheading:2984806-... | lld:pubmed |
| pubmed-article:2984806 | pubmed:meshHeading | pubmed-meshheading:2984806-... | lld:pubmed |
| pubmed-article:2984806 | pubmed:meshHeading | pubmed-meshheading:2984806-... | lld:pubmed |
| pubmed-article:2984806 | pubmed:meshHeading | pubmed-meshheading:2984806-... | lld:pubmed |
| pubmed-article:2984806 | pubmed:meshHeading | pubmed-meshheading:2984806-... | lld:pubmed |
| pubmed-article:2984806 | pubmed:articleTitle | Toxaphene: accumulation in the adrenal cortex and effect on ACTH-stimulated corticosteroid synthesis in the rat. | lld:pubmed |
| pubmed-article:2984806 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2984806 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:2984806 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2984806 | lld:pubmed |
