| pubmed-article:2970180 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2970180 | lifeskim:mentions | umls-concept:C0152105 | lld:lifeskim |
| pubmed-article:2970180 | lifeskim:mentions | umls-concept:C0005516 | lld:lifeskim |
| pubmed-article:2970180 | lifeskim:mentions | umls-concept:C0027481 | lld:lifeskim |
| pubmed-article:2970180 | lifeskim:mentions | umls-concept:C0037494 | lld:lifeskim |
| pubmed-article:2970180 | lifeskim:mentions | umls-concept:C0312418 | lld:lifeskim |
| pubmed-article:2970180 | lifeskim:mentions | umls-concept:C0085580 | lld:lifeskim |
| pubmed-article:2970180 | lifeskim:mentions | umls-concept:C0231221 | lld:lifeskim |
| pubmed-article:2970180 | lifeskim:mentions | umls-concept:C1306673 | lld:lifeskim |
| pubmed-article:2970180 | lifeskim:mentions | umls-concept:C0036667 | lld:lifeskim |
| pubmed-article:2970180 | pubmed:dateCreated | 1988-9-22 | lld:pubmed |
| pubmed-article:2970180 | pubmed:abstractText | Out of 32 patients (f = 10, m = 22; mean age: 46 +/- 3 years) with untreated essential (primary) hypertension (WHO-classification I-III) and without clinical signs of congestive heart failure or chronic renal failure, 19 showed plasma-ANP base levels above the normal range (greater than 100 pg/ml; normal range: 50 +/- 10 pg/ml). While high sodium loading caused an increase of plasma ANP levels and a concomitant decrease of plasma renin and aldosterone concentrations, low sodium loading caused the opposite pattern of ANP and renin/aldosterone secretion. Some patients with essential hypertension with highly elevated plasma ANP levels (10-20-fold above the normal range) showed an only moderate decrease of ANP and a slight increase of renin under a low sodium diet. Plasma ANP levels were significantly correlated with the heart volume (r = 0.54; p less than 0.05; radiologically determined), the electrocardiographic signs of left ventricular hypertrophy (Sokolow-Lyon index; r = 0.62; p less than 0.05) and with the left atrial diameter (r = 0.34; p less than 0.05; determined by 2-D-echocardiography). We speculate that high levels of plasma ANP in patients with essential hypertension might be interpreted as a compensatory mechanism either for an insufficient excretion of sodium or for myocardial dysfunction. | lld:pubmed |
| pubmed-article:2970180 | pubmed:language | ger | lld:pubmed |
| pubmed-article:2970180 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2970180 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2970180 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2970180 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2970180 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2970180 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2970180 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2970180 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2970180 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2970180 | pubmed:issn | 0300-5860 | lld:pubmed |
| pubmed-article:2970180 | pubmed:author | pubmed-author:KaufmannWW | lld:pubmed |
| pubmed-article:2970180 | pubmed:author | pubmed-author:WambachGG | lld:pubmed |
| pubmed-article:2970180 | pubmed:author | pubmed-author:StimpelMM | lld:pubmed |
| pubmed-article:2970180 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2970180 | pubmed:volume | 77 Suppl 2 | lld:pubmed |
| pubmed-article:2970180 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2970180 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2970180 | pubmed:pagination | 92-8 | lld:pubmed |
| pubmed-article:2970180 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2970180 | pubmed:meshHeading | pubmed-meshheading:2970180-... | lld:pubmed |
| pubmed-article:2970180 | pubmed:meshHeading | pubmed-meshheading:2970180-... | lld:pubmed |
| pubmed-article:2970180 | pubmed:meshHeading | pubmed-meshheading:2970180-... | lld:pubmed |
| pubmed-article:2970180 | pubmed:meshHeading | pubmed-meshheading:2970180-... | lld:pubmed |
| pubmed-article:2970180 | pubmed:meshHeading | pubmed-meshheading:2970180-... | lld:pubmed |
| pubmed-article:2970180 | pubmed:meshHeading | pubmed-meshheading:2970180-... | lld:pubmed |
| pubmed-article:2970180 | pubmed:meshHeading | pubmed-meshheading:2970180-... | lld:pubmed |
| pubmed-article:2970180 | pubmed:meshHeading | pubmed-meshheading:2970180-... | lld:pubmed |
| pubmed-article:2970180 | pubmed:meshHeading | pubmed-meshheading:2970180-... | lld:pubmed |
| pubmed-article:2970180 | pubmed:meshHeading | pubmed-meshheading:2970180-... | lld:pubmed |
| pubmed-article:2970180 | pubmed:meshHeading | pubmed-meshheading:2970180-... | lld:pubmed |
| pubmed-article:2970180 | pubmed:meshHeading | pubmed-meshheading:2970180-... | lld:pubmed |
| pubmed-article:2970180 | pubmed:meshHeading | pubmed-meshheading:2970180-... | lld:pubmed |
| pubmed-article:2970180 | pubmed:meshHeading | pubmed-meshheading:2970180-... | lld:pubmed |
| pubmed-article:2970180 | pubmed:meshHeading | pubmed-meshheading:2970180-... | lld:pubmed |
| pubmed-article:2970180 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:2970180 | pubmed:articleTitle | [Atrial natriuretic peptide (ANP) in essential hypertension: a humoral marker for salt sensitivity and hypertensive heart disease at a clinically asymptomatic stage?]. | lld:pubmed |
| pubmed-article:2970180 | pubmed:affiliation | Medizinische Klinik II, Universität Köln, Krankenanstalten Köln-Merheim. | lld:pubmed |
| pubmed-article:2970180 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2970180 | pubmed:publicationType | English Abstract | lld:pubmed |
