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pubmed-article:2943662pubmed:abstractTextThe chromosomal localization of a unique DNA fragment, closely linked to Huntington disease (HD), was assessed in situ by hybridization with 2-acetylaminofluorene (AAF) modified probes. In these experiments, a cosmid cloned genomic fragment (c5.5) was used for hybridization. Here we present evidence that confirms the mapping of the D4S10 locus to the p16 region of chromosome 4 and assigns it to the telomere of the short arm.lld:pubmed
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pubmed-article:2943662pubmed:articleTitleFine mapping of the Huntington disease linked D4S10 locus by non-radioactive in situ hybridization.lld:pubmed
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