| pubmed-article:2875473 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2875473 | lifeskim:mentions | umls-concept:C0020944 | lld:lifeskim |
| pubmed-article:2875473 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:2875473 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:2875473 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:2875473 | lifeskim:mentions | umls-concept:C0205178 | lld:lifeskim |
| pubmed-article:2875473 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:2875473 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:2875473 | lifeskim:mentions | umls-concept:C0205349 | lld:lifeskim |
| pubmed-article:2875473 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:2875473 | pubmed:dateCreated | 1986-10-16 | lld:pubmed |
| pubmed-article:2875473 | pubmed:abstractText | Social isolation results in dynamic changes of neurobiological functions. The altered internal state of the CNS is reflected in changes in spontaneous behavior, changed responses to transmission-related substances and changed responsiveness to an additional impairment of normal relations between the organism and its environment. We analysed the influence of an acute 2-hour immobilization on such isolation-dependent changes. Whereas the susceptibility to pentetrazole-induced seizures increased continuously with lengthening of isolation and was not affected by the additional impairment, the responsiveness to transmission-related substances changed dynamically depending upon isolation-induced alterations. An immobilization-induced increase in responsiveness to LSD and propranolol was demonstrable in grouped controls and after short-term isolation. The apomorphine stimulation during prolonged isolation experienced a down- and an upregulation which were repeated in a stronger manner by immobilization responses especially after long-term isolation. It is suggested that the dynamics of isolation-induced changes coincided with changed acute adaptive functions. | lld:pubmed |
| pubmed-article:2875473 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2875473 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2875473 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2875473 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2875473 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2875473 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2875473 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2875473 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2875473 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2875473 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:2875473 | pubmed:issn | 0091-3057 | lld:pubmed |
| pubmed-article:2875473 | pubmed:author | pubmed-author:SchmidtJJ | lld:pubmed |
| pubmed-article:2875473 | pubmed:author | pubmed-author:OehlerJJ | lld:pubmed |
| pubmed-article:2875473 | pubmed:author | pubmed-author:JähkelMM | lld:pubmed |
| pubmed-article:2875473 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2875473 | pubmed:volume | 25 | lld:pubmed |
| pubmed-article:2875473 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2875473 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2875473 | pubmed:pagination | 41-4 | lld:pubmed |
| pubmed-article:2875473 | pubmed:dateRevised | 2005-11-17 | lld:pubmed |
| pubmed-article:2875473 | pubmed:meshHeading | pubmed-meshheading:2875473-... | lld:pubmed |
| pubmed-article:2875473 | pubmed:meshHeading | pubmed-meshheading:2875473-... | lld:pubmed |
| pubmed-article:2875473 | pubmed:meshHeading | pubmed-meshheading:2875473-... | lld:pubmed |
| pubmed-article:2875473 | pubmed:meshHeading | pubmed-meshheading:2875473-... | lld:pubmed |
| pubmed-article:2875473 | pubmed:meshHeading | pubmed-meshheading:2875473-... | lld:pubmed |
| pubmed-article:2875473 | pubmed:meshHeading | pubmed-meshheading:2875473-... | lld:pubmed |
| pubmed-article:2875473 | pubmed:meshHeading | pubmed-meshheading:2875473-... | lld:pubmed |
| pubmed-article:2875473 | pubmed:meshHeading | pubmed-meshheading:2875473-... | lld:pubmed |
| pubmed-article:2875473 | pubmed:meshHeading | pubmed-meshheading:2875473-... | lld:pubmed |
| pubmed-article:2875473 | pubmed:meshHeading | pubmed-meshheading:2875473-... | lld:pubmed |
| pubmed-article:2875473 | pubmed:meshHeading | pubmed-meshheading:2875473-... | lld:pubmed |
| pubmed-article:2875473 | pubmed:meshHeading | pubmed-meshheading:2875473-... | lld:pubmed |
| pubmed-article:2875473 | pubmed:meshHeading | pubmed-meshheading:2875473-... | lld:pubmed |
| pubmed-article:2875473 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:2875473 | pubmed:articleTitle | Altered neurobiological responses to acute immobilization in social-isolated mice. | lld:pubmed |
| pubmed-article:2875473 | pubmed:publicationType | Journal Article | lld:pubmed |
