| pubmed-article:2869755 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2869755 | lifeskim:mentions | umls-concept:C0237868 | lld:lifeskim |
| pubmed-article:2869755 | lifeskim:mentions | umls-concept:C0006104 | lld:lifeskim |
| pubmed-article:2869755 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
| pubmed-article:2869755 | lifeskim:mentions | umls-concept:C1179435 | lld:lifeskim |
| pubmed-article:2869755 | lifeskim:mentions | umls-concept:C0012472 | lld:lifeskim |
| pubmed-article:2869755 | lifeskim:mentions | umls-concept:C0086376 | lld:lifeskim |
| pubmed-article:2869755 | lifeskim:mentions | umls-concept:C0036679 | lld:lifeskim |
| pubmed-article:2869755 | lifeskim:mentions | umls-concept:C1705248 | lld:lifeskim |
| pubmed-article:2869755 | lifeskim:mentions | umls-concept:C1314939 | lld:lifeskim |
| pubmed-article:2869755 | lifeskim:mentions | umls-concept:C1548799 | lld:lifeskim |
| pubmed-article:2869755 | lifeskim:mentions | umls-concept:C1524073 | lld:lifeskim |
| pubmed-article:2869755 | lifeskim:mentions | umls-concept:C0449432 | lld:lifeskim |
| pubmed-article:2869755 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:2869755 | pubmed:dateCreated | 1986-4-10 | lld:pubmed |
| pubmed-article:2869755 | pubmed:abstractText | The specific binding protein for prostaglandin (PG) E2 solubilized from porcine brain was sensitive to guanine nucleotides. GTP inhibited the association and enhanced the dissociation of the specific [3H]PGE2 binding. Scatchard analyses showed that GTP (10 microM) decreased the binding affinity more than 3-fold without major change in the number of binding site. Gel filtration separated the binding site from GTP-regulatory component (N). The separated binding protein had a reduced affinity to PGE2 and lost its sensitivity to GTP. The addition of the separated N restored its responsiveness to GTP, and also increased the binding affinity to the original level. These results provide direct evidence for the molecular interaction between the PGE2 binding protein and N in the brain. | lld:pubmed |
| pubmed-article:2869755 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2869755 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2869755 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2869755 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2869755 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2869755 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2869755 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2869755 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2869755 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2869755 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2869755 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2869755 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2869755 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:2869755 | pubmed:issn | 0006-291X | lld:pubmed |
| pubmed-article:2869755 | pubmed:author | pubmed-author:WatanabeYY | lld:pubmed |
| pubmed-article:2869755 | pubmed:author | pubmed-author:HayaishiOO | lld:pubmed |
| pubmed-article:2869755 | pubmed:author | pubmed-author:HatanakaMM | lld:pubmed |
| pubmed-article:2869755 | pubmed:author | pubmed-author:YumotoNN | lld:pubmed |
| pubmed-article:2869755 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2869755 | pubmed:day | 26 | lld:pubmed |
| pubmed-article:2869755 | pubmed:volume | 135 | lld:pubmed |
| pubmed-article:2869755 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2869755 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2869755 | pubmed:pagination | 282-9 | lld:pubmed |
| pubmed-article:2869755 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:2869755 | pubmed:meshHeading | pubmed-meshheading:2869755-... | lld:pubmed |
| pubmed-article:2869755 | pubmed:meshHeading | pubmed-meshheading:2869755-... | lld:pubmed |
| pubmed-article:2869755 | pubmed:meshHeading | pubmed-meshheading:2869755-... | lld:pubmed |
| pubmed-article:2869755 | pubmed:meshHeading | pubmed-meshheading:2869755-... | lld:pubmed |
| pubmed-article:2869755 | pubmed:meshHeading | pubmed-meshheading:2869755-... | lld:pubmed |
| pubmed-article:2869755 | pubmed:meshHeading | pubmed-meshheading:2869755-... | lld:pubmed |
| pubmed-article:2869755 | pubmed:meshHeading | pubmed-meshheading:2869755-... | lld:pubmed |
| pubmed-article:2869755 | pubmed:meshHeading | pubmed-meshheading:2869755-... | lld:pubmed |
| pubmed-article:2869755 | pubmed:meshHeading | pubmed-meshheading:2869755-... | lld:pubmed |
| pubmed-article:2869755 | pubmed:meshHeading | pubmed-meshheading:2869755-... | lld:pubmed |
| pubmed-article:2869755 | pubmed:meshHeading | pubmed-meshheading:2869755-... | lld:pubmed |
| pubmed-article:2869755 | pubmed:meshHeading | pubmed-meshheading:2869755-... | lld:pubmed |
| pubmed-article:2869755 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:2869755 | pubmed:articleTitle | Involvement of GTP-regulatory protein in brain prostaglandin E2 receptor and separation of the two components. | lld:pubmed |
| pubmed-article:2869755 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2869755 | lld:pubmed |
