| pubmed-article:2833333 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2833333 | lifeskim:mentions | umls-concept:C0000742 | lld:lifeskim |
| pubmed-article:2833333 | lifeskim:mentions | umls-concept:C0042769 | lld:lifeskim |
| pubmed-article:2833333 | lifeskim:mentions | umls-concept:C0229601 | lld:lifeskim |
| pubmed-article:2833333 | lifeskim:mentions | umls-concept:C0439158 | lld:lifeskim |
| pubmed-article:2833333 | lifeskim:mentions | umls-concept:C1522492 | lld:lifeskim |
| pubmed-article:2833333 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:2833333 | pubmed:dateCreated | 1988-5-17 | lld:pubmed |
| pubmed-article:2833333 | pubmed:abstractText | Yolk-sac-derived hematopoietic cells were infected with a helper-free stock of Abelson virus (A-MuLV). After infection, cells were plated in a clonogenic methylcellulose culture in the absence of exogenous growth factors such as interleukin 3 (IL 3) and erythropoietin (Epo). No colonies were observed in cultures without viral infection, whereas factor-independent colonies were consistently observed with virus-infected cultures. The number of colonies was linearly correlated with the number of cells plated. Erythroid-mix colonies consisting mostly of erythroblasts, macrophages, and mast cells could be observed. Tumorigenic, continuously growing mast cell lines could be generated at high frequency from these erythroid-mix colonies after they were initially passaged in the presence of an irradiated feeder layer for 4 to 8 weeks. Southern blot analysis of the DNA from five of these lines examined were all shown to contain integrated A-MuLV proviral DNA. These data are evidence that A-MuLV can directly infect embryonic multipotent hematopoietic progenitor cells and drive them to differentiate to various progeny cells without exogenous growth factors. | lld:pubmed |
| pubmed-article:2833333 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2833333 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2833333 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:2833333 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2833333 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2833333 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:2833333 | pubmed:issn | 0006-4971 | lld:pubmed |
| pubmed-article:2833333 | pubmed:author | pubmed-author:RuscettiSS | lld:pubmed |
| pubmed-article:2833333 | pubmed:author | pubmed-author:ChengC WCW | lld:pubmed |
| pubmed-article:2833333 | pubmed:author | pubmed-author:WongP MPM | lld:pubmed |
| pubmed-article:2833333 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2833333 | pubmed:volume | 71 | lld:pubmed |
| pubmed-article:2833333 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2833333 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2833333 | pubmed:pagination | 973-7 | lld:pubmed |
| pubmed-article:2833333 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2833333 | pubmed:meshHeading | pubmed-meshheading:2833333-... | lld:pubmed |
| pubmed-article:2833333 | pubmed:meshHeading | pubmed-meshheading:2833333-... | lld:pubmed |
| pubmed-article:2833333 | pubmed:meshHeading | pubmed-meshheading:2833333-... | lld:pubmed |
| pubmed-article:2833333 | pubmed:meshHeading | pubmed-meshheading:2833333-... | lld:pubmed |
| pubmed-article:2833333 | pubmed:meshHeading | pubmed-meshheading:2833333-... | lld:pubmed |
| pubmed-article:2833333 | pubmed:meshHeading | pubmed-meshheading:2833333-... | lld:pubmed |
| pubmed-article:2833333 | pubmed:meshHeading | pubmed-meshheading:2833333-... | lld:pubmed |
| pubmed-article:2833333 | pubmed:meshHeading | pubmed-meshheading:2833333-... | lld:pubmed |
| pubmed-article:2833333 | pubmed:meshHeading | pubmed-meshheading:2833333-... | lld:pubmed |
| pubmed-article:2833333 | pubmed:meshHeading | pubmed-meshheading:2833333-... | lld:pubmed |
| pubmed-article:2833333 | pubmed:meshHeading | pubmed-meshheading:2833333-... | lld:pubmed |
| pubmed-article:2833333 | pubmed:meshHeading | pubmed-meshheading:2833333-... | lld:pubmed |
| pubmed-article:2833333 | pubmed:meshHeading | pubmed-meshheading:2833333-... | lld:pubmed |
| pubmed-article:2833333 | pubmed:meshHeading | pubmed-meshheading:2833333-... | lld:pubmed |
| pubmed-article:2833333 | pubmed:meshHeading | pubmed-meshheading:2833333-... | lld:pubmed |
| pubmed-article:2833333 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:2833333 | pubmed:articleTitle | Formation of factor-independent hematopoietic multilineage colonies after Abelson virus infection. | lld:pubmed |
| pubmed-article:2833333 | pubmed:affiliation | Laboratory of Genetics, National Cancer Institute, Bethesda, MD 20892. | lld:pubmed |
| pubmed-article:2833333 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2833333 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2833333 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2833333 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2833333 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2833333 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2833333 | lld:pubmed |
