| pubmed-article:2825424 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2825424 | lifeskim:mentions | umls-concept:C0206679 | lld:lifeskim |
| pubmed-article:2825424 | lifeskim:mentions | umls-concept:C0012939 | lld:lifeskim |
| pubmed-article:2825424 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:2825424 | lifeskim:mentions | umls-concept:C0598312 | lld:lifeskim |
| pubmed-article:2825424 | lifeskim:mentions | umls-concept:C1823153 | lld:lifeskim |
| pubmed-article:2825424 | lifeskim:mentions | umls-concept:C2349976 | lld:lifeskim |
| pubmed-article:2825424 | lifeskim:mentions | umls-concept:C1552644 | lld:lifeskim |
| pubmed-article:2825424 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:2825424 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2825424 | pubmed:dateCreated | 1988-1-21 | lld:pubmed |
| pubmed-article:2825424 | pubmed:abstractText | The expression of gamma 2 or true gamma genes resident in the herpes simplex virus 1 genome requires functional products of genes expressed earlier in infection and viral DNA synthesis. To determine whether the requirement for viral DNA synthesis for the expression of gamma 2 genes reflects a trans-acting function of a product of one or a few genes made or activated during viral DNA synthesis or whether it reflects a cis effect of DNA synthesis at specific sites, 143 thymidine kinase (TK) minus cells were sequentially infected with a virus carrying a 700-bp deletion of the TK gene and 6 hr later with wild-type or recombinant viruses carrying an alpha-TK or a gamma 2-TK gene in either the presence or absence of viral DNA synthesis. These experiments indicated that the gamma 2-TK gene contained in an unreplicated viral genome was not expressed by trans-acting factors specified before and during DNA synthesis by the first infecting virus, and, therefore, the induction of gamma 2 genes appears to be mediated by a cis-acting function associated with viral DNA synthesis. | lld:pubmed |
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| pubmed-article:2825424 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2825424 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2825424 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2825424 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2825424 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2825424 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:2825424 | pubmed:issn | 0042-6822 | lld:pubmed |
| pubmed-article:2825424 | pubmed:author | pubmed-author:RoizmanBB | lld:pubmed |
| pubmed-article:2825424 | pubmed:author | pubmed-author:Mavromara-Naz... | lld:pubmed |
| pubmed-article:2825424 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2825424 | pubmed:volume | 161 | lld:pubmed |
| pubmed-article:2825424 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2825424 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2825424 | pubmed:pagination | 593-8 | lld:pubmed |
| pubmed-article:2825424 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:2825424 | pubmed:meshHeading | pubmed-meshheading:2825424-... | lld:pubmed |
| pubmed-article:2825424 | pubmed:meshHeading | pubmed-meshheading:2825424-... | lld:pubmed |
| pubmed-article:2825424 | pubmed:meshHeading | pubmed-meshheading:2825424-... | lld:pubmed |
| pubmed-article:2825424 | pubmed:meshHeading | pubmed-meshheading:2825424-... | lld:pubmed |
| pubmed-article:2825424 | pubmed:meshHeading | pubmed-meshheading:2825424-... | lld:pubmed |
| pubmed-article:2825424 | pubmed:meshHeading | pubmed-meshheading:2825424-... | lld:pubmed |
| pubmed-article:2825424 | pubmed:meshHeading | pubmed-meshheading:2825424-... | lld:pubmed |
| pubmed-article:2825424 | pubmed:meshHeading | pubmed-meshheading:2825424-... | lld:pubmed |
| pubmed-article:2825424 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:2825424 | pubmed:articleTitle | Activation of herpes simplex virus 1 gamma 2 genes by viral DNA replication. | lld:pubmed |
| pubmed-article:2825424 | pubmed:affiliation | Marjorie B. Kovler Viral Oncology Laboratories, University of Chicago, Illinois 60637. | lld:pubmed |
| pubmed-article:2825424 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2825424 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2825424 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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