| pubmed-article:2818863 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2818863 | lifeskim:mentions | umls-concept:C0028948 | lld:lifeskim |
| pubmed-article:2818863 | lifeskim:mentions | umls-concept:C0043442 | lld:lifeskim |
| pubmed-article:2818863 | lifeskim:mentions | umls-concept:C0600436 | lld:lifeskim |
| pubmed-article:2818863 | lifeskim:mentions | umls-concept:C0026377 | lld:lifeskim |
| pubmed-article:2818863 | lifeskim:mentions | umls-concept:C0008813 | lld:lifeskim |
| pubmed-article:2818863 | lifeskim:mentions | umls-concept:C0332256 | lld:lifeskim |
| pubmed-article:2818863 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:2818863 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:2818863 | pubmed:dateCreated | 1989-12-26 | lld:pubmed |
| pubmed-article:2818863 | pubmed:abstractText | A number of fully self-complementary oligodeoxynucleotides have been synthesized and examined for their ability to assume the left-handed Z-DNA conformation in high salt solutions. The B- and Z-forms are identified by circular dichroism spectra, covering both the long- (220-300 nm) and short-wavelength (185-220 nm) regions, the latter showing CD bands very useful for identifying the sense of the helix winding. The main results of the study can be summarized as follows: a) sequences composed by AT and CG blocks do support the B to Z transition, even when the AT contents amounts to 50%; b) the occurrence of consecutive purine-purine or pyrimidine-pyrimidine dyads does not inhibit the B to Z transition, although a stronger reduction of water activity is required; c) (AC)n and (GT)n containing oligonucleotides do undergo the B to Z transition in solution; d) a millimolar quantity of Ni2+ concomitant with 5 M NaClO4 is found to be very effective in bringing about the B to Z transition in most of the sequences considered in this study. | lld:pubmed |
| pubmed-article:2818863 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2818863 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2818863 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2818863 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2818863 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2818863 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2818863 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2818863 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2818863 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:2818863 | pubmed:issn | 0739-1102 | lld:pubmed |
| pubmed-article:2818863 | pubmed:author | pubmed-author:van BoomJ HJH | lld:pubmed |
| pubmed-article:2818863 | pubmed:author | pubmed-author:YathindraNN | lld:pubmed |
| pubmed-article:2818863 | pubmed:author | pubmed-author:ManziniGG | lld:pubmed |
| pubmed-article:2818863 | pubmed:author | pubmed-author:QuadrifoglioF... | lld:pubmed |
| pubmed-article:2818863 | pubmed:author | pubmed-author:van der... | lld:pubmed |
| pubmed-article:2818863 | pubmed:author | pubmed-author:XodoL ELE | lld:pubmed |
| pubmed-article:2818863 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2818863 | pubmed:volume | 6 | lld:pubmed |
| pubmed-article:2818863 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2818863 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2818863 | pubmed:pagination | 1217-31 | lld:pubmed |
| pubmed-article:2818863 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2818863 | pubmed:meshHeading | pubmed-meshheading:2818863-... | lld:pubmed |
| pubmed-article:2818863 | pubmed:meshHeading | pubmed-meshheading:2818863-... | lld:pubmed |
| pubmed-article:2818863 | pubmed:meshHeading | pubmed-meshheading:2818863-... | lld:pubmed |
| pubmed-article:2818863 | pubmed:meshHeading | pubmed-meshheading:2818863-... | lld:pubmed |
| pubmed-article:2818863 | pubmed:meshHeading | pubmed-meshheading:2818863-... | lld:pubmed |
| pubmed-article:2818863 | pubmed:meshHeading | pubmed-meshheading:2818863-... | lld:pubmed |
| pubmed-article:2818863 | pubmed:meshHeading | pubmed-meshheading:2818863-... | lld:pubmed |
| pubmed-article:2818863 | pubmed:meshHeading | pubmed-meshheading:2818863-... | lld:pubmed |
| pubmed-article:2818863 | pubmed:meshHeading | pubmed-meshheading:2818863-... | lld:pubmed |
| pubmed-article:2818863 | pubmed:meshHeading | pubmed-meshheading:2818863-... | lld:pubmed |
| pubmed-article:2818863 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2818863 | pubmed:articleTitle | The left-handed Z-DNA conformation in oligodeoxynucleotides containing different amounts of AT base pairs: a far UV circular dichroism study. | lld:pubmed |
| pubmed-article:2818863 | pubmed:affiliation | Department of Biochemistry, Biophysics and Macromolecular Chemistry, University of Trieste, Italy. | lld:pubmed |
| pubmed-article:2818863 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2818863 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2818863 | lld:pubmed |
