pubmed-article:2731164 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2731164 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
pubmed-article:2731164 | lifeskim:mentions | umls-concept:C0039601 | lld:lifeskim |
pubmed-article:2731164 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:2731164 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
pubmed-article:2731164 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:2731164 | pubmed:dateCreated | 1989-7-21 | lld:pubmed |
pubmed-article:2731164 | pubmed:abstractText | Large metastasizing prostate adenocarcinomas (PAs) were induced in L-W rats by a single intravenous (i.v.) inoculation of methylnitrosourea (MNU) and then single subcutaneous implants of testosterone propionate (TP) at intervals of 2 months. This procedure induced PAs in approximately 90% of rats in an average of 11 months. PAs did not develop spontaneously in L-W rats under age 20 months. With this model system, it was demonstrated that within a 14-month observation period, significant numbers of PAs were elicited by TP implants in L-W rats after intervals of 1 week, 1 month and 2 months following the inoculation of MNU. A direct relationship was also demonstrated between amount of TP administered to L-W rats and the resulting incidence of PAs. TP is characterized as a prostate-directed promoter of PA, following a single inoculation of MNU which served as the tumor initiator. | lld:pubmed |
pubmed-article:2731164 | pubmed:language | eng | lld:pubmed |
pubmed-article:2731164 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2731164 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2731164 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2731164 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2731164 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2731164 | pubmed:month | Jun | lld:pubmed |
pubmed-article:2731164 | pubmed:issn | 0304-3835 | lld:pubmed |
pubmed-article:2731164 | pubmed:author | pubmed-author:PollardMM | lld:pubmed |
pubmed-article:2731164 | pubmed:author | pubmed-author:LuckertP HPH | lld:pubmed |
pubmed-article:2731164 | pubmed:author | pubmed-author:SnyderD LDL | lld:pubmed |
pubmed-article:2731164 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2731164 | pubmed:volume | 45 | lld:pubmed |
pubmed-article:2731164 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2731164 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2731164 | pubmed:pagination | 209-12 | lld:pubmed |
pubmed-article:2731164 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:2731164 | pubmed:meshHeading | pubmed-meshheading:2731164-... | lld:pubmed |
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pubmed-article:2731164 | pubmed:meshHeading | pubmed-meshheading:2731164-... | lld:pubmed |
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pubmed-article:2731164 | pubmed:meshHeading | pubmed-meshheading:2731164-... | lld:pubmed |
pubmed-article:2731164 | pubmed:year | 1989 | lld:pubmed |
pubmed-article:2731164 | pubmed:articleTitle | The promotional effect of testosterone on induction of prostate-cancer in MNU-sensitized L-W rats. | lld:pubmed |
pubmed-article:2731164 | pubmed:affiliation | Lobund Laboratory, University of Notre Dame, IN 46556. | lld:pubmed |
pubmed-article:2731164 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2731164 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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