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pubmed-article:2697138pubmed:abstractTextRecent evidence suggests that copper exacts an important role in the maintenance of immunocompetence. Copper deficiency results in decreased humoral and cell-mediated, as well as nonspecific immune function. Impairment of immune function may be highly correlated with an increased incidence of infection and higher mortality rates observed in copper-deficient animals. The actual mechanisms by which copper is involved in immune processes are not well defined. This review addresses the copper-immune function interaction and discusses possible immunomodulatory roles for copper.lld:pubmed
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pubmed-article:2697138pubmed:authorpubmed-author:SpearsJ WJWlld:pubmed
pubmed-article:2697138pubmed:authorpubmed-author:StabelJ RJRlld:pubmed
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pubmed-article:2697138pubmed:volume258lld:pubmed
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pubmed-article:2697138pubmed:pagination243-52lld:pubmed
pubmed-article:2697138pubmed:dateRevised2005-11-16lld:pubmed
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pubmed-article:2697138pubmed:year1989lld:pubmed
pubmed-article:2697138pubmed:articleTitleEffect of copper on immune function and disease resistance.lld:pubmed
pubmed-article:2697138pubmed:affiliationNational Animal Disease Center, USDA Agricultural Research Service, Ames, IA 50010.lld:pubmed
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