| pubmed-article:2656254 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2656254 | lifeskim:mentions | umls-concept:C0206273 | lld:lifeskim |
| pubmed-article:2656254 | lifeskim:mentions | umls-concept:C0032098 | lld:lifeskim |
| pubmed-article:2656254 | lifeskim:mentions | umls-concept:C0017428 | lld:lifeskim |
| pubmed-article:2656254 | lifeskim:mentions | umls-concept:C0030946 | lld:lifeskim |
| pubmed-article:2656254 | lifeskim:mentions | umls-concept:C2700640 | lld:lifeskim |
| pubmed-article:2656254 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2656254 | pubmed:dateCreated | 1989-6-29 | lld:pubmed |
| pubmed-article:2656254 | pubmed:abstractText | The RNA genome of tobacco etch virus (TEV) encodes a large polyprotein precursor that is processed to mature proteins by virus-specific proteinases. Cleavage sites located within the carboxyl-terminal two-thirds of the polyprotein are processed by a TEV-encoded 49 kd proteinase, while the enzyme(s) responsible for cleaving the remaining sites has not been found. In this study, a second TEV-encoded proteinase has been identified based on cell-free expression of defined RNA transcripts. The boundaries of this proteinase have been delineated by deletion analysis and site-directed mutagenesis. The proteolytically active domain has been localized to the carboxyl-terminal half of the 56 kd aphid-transmission helper component. A cleavage site that is recognized by this proteinase has been identified in the polyprotein adjacent to the carboxyl-terminus of the enzyme, and the proteinase appears to cleave by an autocatalytic mechanism. Proteolysis in vitro occurs between a Gly-Gly dipeptide as determined by radiochemical sequencing at the amino-terminus of the proteolytic product. | lld:pubmed |
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| pubmed-article:2656254 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2656254 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2656254 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2656254 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2656254 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:2656254 | pubmed:issn | 0261-4189 | lld:pubmed |
| pubmed-article:2656254 | pubmed:author | pubmed-author:CarrS HSH | lld:pubmed |
| pubmed-article:2656254 | pubmed:author | pubmed-author:CarringtonJ... | lld:pubmed |
| pubmed-article:2656254 | pubmed:author | pubmed-author:DoughertyW... | lld:pubmed |
| pubmed-article:2656254 | pubmed:author | pubmed-author:ParksT DTD | lld:pubmed |
| pubmed-article:2656254 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2656254 | pubmed:volume | 8 | lld:pubmed |
| pubmed-article:2656254 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2656254 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2656254 | pubmed:pagination | 365-70 | lld:pubmed |
| pubmed-article:2656254 | pubmed:dateRevised | 2010-9-9 | lld:pubmed |
| pubmed-article:2656254 | pubmed:meshHeading | pubmed-meshheading:2656254-... | lld:pubmed |
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| pubmed-article:2656254 | pubmed:meshHeading | pubmed-meshheading:2656254-... | lld:pubmed |
| pubmed-article:2656254 | pubmed:meshHeading | pubmed-meshheading:2656254-... | lld:pubmed |
| pubmed-article:2656254 | pubmed:meshHeading | pubmed-meshheading:2656254-... | lld:pubmed |
| pubmed-article:2656254 | pubmed:meshHeading | pubmed-meshheading:2656254-... | lld:pubmed |
| pubmed-article:2656254 | pubmed:meshHeading | pubmed-meshheading:2656254-... | lld:pubmed |
| pubmed-article:2656254 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2656254 | pubmed:articleTitle | A second proteinase encoded by a plant potyvirus genome. | lld:pubmed |
| pubmed-article:2656254 | pubmed:affiliation | Department of Biology, Texas A&M University, College Station 77843. | lld:pubmed |
| pubmed-article:2656254 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2656254 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2656254 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:2656254 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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