| pubmed-article:2565884 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2565884 | lifeskim:mentions | umls-concept:C0025932 | lld:lifeskim |
| pubmed-article:2565884 | lifeskim:mentions | umls-concept:C0021853 | lld:lifeskim |
| pubmed-article:2565884 | lifeskim:mentions | umls-concept:C0079720 | lld:lifeskim |
| pubmed-article:2565884 | lifeskim:mentions | umls-concept:C0034790 | lld:lifeskim |
| pubmed-article:2565884 | lifeskim:mentions | umls-concept:C0205307 | lld:lifeskim |
| pubmed-article:2565884 | lifeskim:mentions | umls-concept:C0597360 | lld:lifeskim |
| pubmed-article:2565884 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:2565884 | pubmed:dateCreated | 1989-6-19 | lld:pubmed |
| pubmed-article:2565884 | pubmed:abstractText | Intra-epithelial lymphocytes (IEL) in murine small intestine were analysed for the presence of cell-surface antigens and T-cell receptor allotype in normal and athymic BALB/c mice by immunoperoxidase histochemistry on frozen sections and immunofluorescence on isolated IEL. In frozen sections, IEL of normal mice were 97.7% CD45+, 93.5% CD3+, 46.2% Thy-1+, 91.1% CD8+, 10.7% CD4+ and 21.1% KJ16+ (V beta 8.1 and 8.2). FACS analysis of isolated IEL confirmed the level of KJ16 expression and also demonstrated that 25% of IEL were F23.1+ (V beta 8.1-8.3). Immunofluorescent double-staining revealed a skewed distribution of T-cell receptor (TcR) expression on Thy-1+ and Thy-1- IEL. KJ16 and F23.1 were expressed on 25.9% and 32.7% of Thy-1+ IEL, respectively; however, the frequency of V beta 8 expression was diminished on Thy-1- IEL (4.1% KJ16+ and 12.1% F23.1+). IEL are present in athymic mice, but at reduced levels. In frozen sections these cells were 91.9% CD45+, 69.5% CD3+, less than 1% Thy-1+, 83.6% CD8+, less than 1% CD4+ and less than 1% KJ16+. Thus it appears that in normal mice there may be two distinct lineages of IEL, a thymus-dependent Thy-1+ population which utilizes the alpha beta T-cell receptor and a thymus-independent Thy-1- population (represented in athymic mice), which may possibly utilize the alternative gamma delta TcR. | lld:pubmed |
| pubmed-article:2565884 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2565884 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2565884 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565884 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2565884 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:2565884 | pubmed:issn | 0019-2805 | lld:pubmed |
| pubmed-article:2565884 | pubmed:author | pubmed-author:MacDonaldT... | lld:pubmed |
| pubmed-article:2565884 | pubmed:author | pubmed-author:KilshawP JPJ | lld:pubmed |
| pubmed-article:2565884 | pubmed:author | pubmed-author:VineyJ LJL | lld:pubmed |
| pubmed-article:2565884 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2565884 | pubmed:volume | 66 | lld:pubmed |
| pubmed-article:2565884 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2565884 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2565884 | pubmed:pagination | 583-7 | lld:pubmed |
| pubmed-article:2565884 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:2565884 | pubmed:meshHeading | pubmed-meshheading:2565884-... | lld:pubmed |
| pubmed-article:2565884 | pubmed:meshHeading | pubmed-meshheading:2565884-... | lld:pubmed |
| pubmed-article:2565884 | pubmed:meshHeading | pubmed-meshheading:2565884-... | lld:pubmed |
| pubmed-article:2565884 | pubmed:meshHeading | pubmed-meshheading:2565884-... | lld:pubmed |
| pubmed-article:2565884 | pubmed:meshHeading | pubmed-meshheading:2565884-... | lld:pubmed |
| pubmed-article:2565884 | pubmed:meshHeading | pubmed-meshheading:2565884-... | lld:pubmed |
| pubmed-article:2565884 | pubmed:meshHeading | pubmed-meshheading:2565884-... | lld:pubmed |
| pubmed-article:2565884 | pubmed:meshHeading | pubmed-meshheading:2565884-... | lld:pubmed |
| pubmed-article:2565884 | pubmed:meshHeading | pubmed-meshheading:2565884-... | lld:pubmed |
| pubmed-article:2565884 | pubmed:meshHeading | pubmed-meshheading:2565884-... | lld:pubmed |
| pubmed-article:2565884 | pubmed:meshHeading | pubmed-meshheading:2565884-... | lld:pubmed |
| pubmed-article:2565884 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2565884 | pubmed:articleTitle | T-cell receptor expression in intestinal intra-epithelial lymphocyte subpopulations of normal and athymic mice. | lld:pubmed |
| pubmed-article:2565884 | pubmed:affiliation | Department of Paediatric Gastroenterology, St Bartholomews Hospital, London. | lld:pubmed |
| pubmed-article:2565884 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2565884 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565884 | lld:pubmed |
