| pubmed-article:2529815 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2529815 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:2529815 | lifeskim:mentions | umls-concept:C0014118 | lld:lifeskim |
| pubmed-article:2529815 | lifeskim:mentions | umls-concept:C0145106 | lld:lifeskim |
| pubmed-article:2529815 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:2529815 | pubmed:dateCreated | 1989-11-13 | lld:pubmed |
| pubmed-article:2529815 | pubmed:abstractText | Intravenous teicoplanin has been used to treat 23 cases of gram-positive-bacterial endocarditis, usually with 3 to 7 mg/kg every 12 h on the first day, followed by 3 to 7 mg/kg every 24 h. For some cases (staphylococcal and enterococcal endocarditis), the dosage was 8 to 14.4 mg/kg per day and/or other antibiotics were given. The mean duration was 48.2 days (range, 23 to 130 days). Of 23 patients, 21 (91.3%) had negative cultures or were cured. A total of 18 patients were treated with teicoplanin alone; of these, 4 had surgery, and all (except 2 who relapsed) were cured. Teicoplanin was combined with one or more antibiotics in five cases; in all cases appropriate cultures were negative, but three patients died during therapy or follow-up. Mild renal impairment was seen in two patients; both were receiving teicoplanin in combination with an aminoglycoside. We conclude that intravenous teicoplanin administered once a day at doses of 7 to 14 mg/kg per day is well tolerated, easy to administer, and may represent an efficacious therapy for gram-positive-bacterial endocarditis. | lld:pubmed |
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| pubmed-article:2529815 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2529815 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2529815 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2529815 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2529815 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:2529815 | pubmed:issn | 0066-4804 | lld:pubmed |
| pubmed-article:2529815 | pubmed:author | pubmed-author:SerraPP | lld:pubmed |
| pubmed-article:2529815 | pubmed:author | pubmed-author:GentileGG | lld:pubmed |
| pubmed-article:2529815 | pubmed:author | pubmed-author:MartinoPP | lld:pubmed |
| pubmed-article:2529815 | pubmed:author | pubmed-author:BrandimarteCC | lld:pubmed |
| pubmed-article:2529815 | pubmed:author | pubmed-author:VendittiMM | lld:pubmed |
| pubmed-article:2529815 | pubmed:author | pubmed-author:MicozziAA | lld:pubmed |
| pubmed-article:2529815 | pubmed:author | pubmed-author:SantiniCC | lld:pubmed |
| pubmed-article:2529815 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2529815 | pubmed:volume | 33 | lld:pubmed |
| pubmed-article:2529815 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2529815 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2529815 | pubmed:pagination | 1329-34 | lld:pubmed |
| pubmed-article:2529815 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:2529815 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2529815 | pubmed:articleTitle | Teicoplanin in the treatment of gram-positive-bacterial endocarditis. | lld:pubmed |
| pubmed-article:2529815 | pubmed:affiliation | Cattedra di Ematologia, Dipartimento di Biopatologia Umana, Rome, Italy. | lld:pubmed |
| pubmed-article:2529815 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2529815 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:2529815 | pubmed:publicationType | Controlled Clinical Trial | lld:pubmed |
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