| pubmed-article:2445404 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2445404 | lifeskim:mentions | umls-concept:C0030274 | lld:lifeskim |
| pubmed-article:2445404 | lifeskim:mentions | umls-concept:C0205101 | lld:lifeskim |
| pubmed-article:2445404 | lifeskim:mentions | umls-concept:C0001480 | lld:lifeskim |
| pubmed-article:2445404 | lifeskim:mentions | umls-concept:C0006945 | lld:lifeskim |
| pubmed-article:2445404 | lifeskim:mentions | umls-concept:C0009647 | lld:lifeskim |
| pubmed-article:2445404 | lifeskim:mentions | umls-concept:C0017725 | lld:lifeskim |
| pubmed-article:2445404 | lifeskim:mentions | umls-concept:C0332157 | lld:lifeskim |
| pubmed-article:2445404 | lifeskim:mentions | umls-concept:C0205156 | lld:lifeskim |
| pubmed-article:2445404 | lifeskim:mentions | umls-concept:C0596233 | lld:lifeskim |
| pubmed-article:2445404 | lifeskim:mentions | umls-concept:C1998548 | lld:lifeskim |
| pubmed-article:2445404 | lifeskim:mentions | umls-concept:C1176299 | lld:lifeskim |
| pubmed-article:2445404 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2445404 | pubmed:dateCreated | 1987-12-24 | lld:pubmed |
| pubmed-article:2445404 | pubmed:abstractText | 1 Exposure to ATP (2-200 microM) resulted in a prominent peak of 45Ca efflux, when beta-cell-rich pancreatic islets from ob/ob-mice were perifused with a Ca2+-deficient medium. ADP and the stable alpha/beta-methylene analogues of ATP and ADP also had stimulatory effects. 2 The nucleotide initiation of 45Ca efflux mimicked that obtained with carbachol both in requiring previous exposure to glucose and in being more pronounced after replacing extracellular Na+ by K+. 3 It was possible to induce repeated peaks of stimulated 45Ca efflux, when the exposure to ATP was interrupted with intervals of perifusion with glucose-containing media. 4 The observations are consistent with the existence of P2-purinoceptors in islets, suggesting that these receptors mediate a similar mobilization of calcium as noted when activating polyphosphoinositide breakdown with carbachol. In view of the high contents of ATP and ADP in the beta-cell secretory granules, activation of P2-purinoceptors should be considered as a possible mechanism for amplification of the initial insulin secretory response. | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2445404 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2445404 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2445404 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2445404 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:2445404 | pubmed:issn | 0007-1188 | lld:pubmed |
| pubmed-article:2445404 | pubmed:author | pubmed-author:HellmanBB | lld:pubmed |
| pubmed-article:2445404 | pubmed:author | pubmed-author:GylfeEE | lld:pubmed |
| pubmed-article:2445404 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2445404 | pubmed:volume | 92 | lld:pubmed |
| pubmed-article:2445404 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2445404 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2445404 | pubmed:pagination | 281-9 | lld:pubmed |
| pubmed-article:2445404 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:2445404 | pubmed:meshHeading | pubmed-meshheading:2445404-... | lld:pubmed |
| pubmed-article:2445404 | pubmed:meshHeading | pubmed-meshheading:2445404-... | lld:pubmed |
| pubmed-article:2445404 | pubmed:meshHeading | pubmed-meshheading:2445404-... | lld:pubmed |
| pubmed-article:2445404 | pubmed:meshHeading | pubmed-meshheading:2445404-... | lld:pubmed |
| pubmed-article:2445404 | pubmed:meshHeading | pubmed-meshheading:2445404-... | lld:pubmed |
| pubmed-article:2445404 | pubmed:meshHeading | pubmed-meshheading:2445404-... | lld:pubmed |
| pubmed-article:2445404 | pubmed:meshHeading | pubmed-meshheading:2445404-... | lld:pubmed |
| pubmed-article:2445404 | pubmed:meshHeading | pubmed-meshheading:2445404-... | lld:pubmed |
| pubmed-article:2445404 | pubmed:meshHeading | pubmed-meshheading:2445404-... | lld:pubmed |
| pubmed-article:2445404 | pubmed:meshHeading | pubmed-meshheading:2445404-... | lld:pubmed |
| pubmed-article:2445404 | pubmed:meshHeading | pubmed-meshheading:2445404-... | lld:pubmed |
| pubmed-article:2445404 | pubmed:meshHeading | pubmed-meshheading:2445404-... | lld:pubmed |
| pubmed-article:2445404 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:2445404 | pubmed:articleTitle | External ATP mimics carbachol in initiating calcium mobilization from pancreatic beta-cells conditioned by previous exposure to glucose. | lld:pubmed |
| pubmed-article:2445404 | pubmed:affiliation | Department of Medical Cell Biology, University of Uppsala, Sweden. | lld:pubmed |
| pubmed-article:2445404 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2445404 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:2445404 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2445404 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2445404 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2445404 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2445404 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2445404 | lld:pubmed |
