| pubmed-article:2416747 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2416747 | lifeskim:mentions | umls-concept:C0026237 | lld:lifeskim |
| pubmed-article:2416747 | lifeskim:mentions | umls-concept:C0013714 | lld:lifeskim |
| pubmed-article:2416747 | lifeskim:mentions | umls-concept:C0030685 | lld:lifeskim |
| pubmed-article:2416747 | lifeskim:mentions | umls-concept:C0596235 | lld:lifeskim |
| pubmed-article:2416747 | lifeskim:mentions | umls-concept:C0680255 | lld:lifeskim |
| pubmed-article:2416747 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:2416747 | lifeskim:mentions | umls-concept:C0391871 | lld:lifeskim |
| pubmed-article:2416747 | lifeskim:mentions | umls-concept:C1283071 | lld:lifeskim |
| pubmed-article:2416747 | lifeskim:mentions | umls-concept:C1963578 | lld:lifeskim |
| pubmed-article:2416747 | lifeskim:mentions | umls-concept:C0439831 | lld:lifeskim |
| pubmed-article:2416747 | lifeskim:mentions | umls-concept:C0205231 | lld:lifeskim |
| pubmed-article:2416747 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:2416747 | pubmed:dateCreated | 1986-2-12 | lld:pubmed |
| pubmed-article:2416747 | pubmed:abstractText | A novel mitochondrial Ca2+ release phenomenon is reported. When rat liver mitochondria (oxidizing succinate) are allowed to accumulate Ca2+ in excess of 40 nmol/mg protein and are then treated with excess EGTA, a fraction of the accumulated cation is rapidly (approximately 1 nmol/s/mg protein) released. The size of the released fraction is an apparent function of the extramitochondrial Ca2+ concentration at the time of EGTA addition and can attain a maximal value of approximately 30 nmol/mg protein. Release is inhibited by ruthenium red (I50 approximately 50 pmol/mg protein) and is not dependent on the presence of Na+ or K+ in the medium. During the period of rapid release, O2 consumption is inhibited, membrane potential increases, and apparent H+ accumulation occurs at a ratio of approximately 2H+ per Ca2+ released. It is proposed that this chelator-induced Ca2+ release occurs by reverse uniport with H+ back diffusion to the matrix space providing charge movement compensation. | lld:pubmed |
| pubmed-article:2416747 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2416747 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2416747 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2416747 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2416747 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2416747 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2416747 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2416747 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2416747 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2416747 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2416747 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2416747 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2416747 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:2416747 | pubmed:issn | 0021-9258 | lld:pubmed |
| pubmed-article:2416747 | pubmed:author | pubmed-author:PfeifferD RDR | lld:pubmed |
| pubmed-article:2416747 | pubmed:author | pubmed-author:RileyW WWWJr | lld:pubmed |
| pubmed-article:2416747 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2416747 | pubmed:day | 5 | lld:pubmed |
| pubmed-article:2416747 | pubmed:volume | 261 | lld:pubmed |
| pubmed-article:2416747 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2416747 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2416747 | pubmed:pagination | 28-31 | lld:pubmed |
| pubmed-article:2416747 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:2416747 | pubmed:meshHeading | pubmed-meshheading:2416747-... | lld:pubmed |
| pubmed-article:2416747 | pubmed:meshHeading | pubmed-meshheading:2416747-... | lld:pubmed |
| pubmed-article:2416747 | pubmed:meshHeading | pubmed-meshheading:2416747-... | lld:pubmed |
| pubmed-article:2416747 | pubmed:meshHeading | pubmed-meshheading:2416747-... | lld:pubmed |
| pubmed-article:2416747 | pubmed:meshHeading | pubmed-meshheading:2416747-... | lld:pubmed |
| pubmed-article:2416747 | pubmed:meshHeading | pubmed-meshheading:2416747-... | lld:pubmed |
| pubmed-article:2416747 | pubmed:meshHeading | pubmed-meshheading:2416747-... | lld:pubmed |
| pubmed-article:2416747 | pubmed:meshHeading | pubmed-meshheading:2416747-... | lld:pubmed |
| pubmed-article:2416747 | pubmed:meshHeading | pubmed-meshheading:2416747-... | lld:pubmed |
| pubmed-article:2416747 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:2416747 | pubmed:articleTitle | Rapid and extensive release of Ca2+ from energized mitochondria induced by EGTA. | lld:pubmed |
| pubmed-article:2416747 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2416747 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2416747 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2416747 | lld:pubmed |
