| pubmed-article:2410524 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2410524 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:2410524 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:2410524 | lifeskim:mentions | umls-concept:C0003250 | lld:lifeskim |
| pubmed-article:2410524 | lifeskim:mentions | umls-concept:C0003241 | lld:lifeskim |
| pubmed-article:2410524 | lifeskim:mentions | umls-concept:C0003591 | lld:lifeskim |
| pubmed-article:2410524 | lifeskim:mentions | umls-concept:C0011740 | lld:lifeskim |
| pubmed-article:2410524 | lifeskim:mentions | umls-concept:C1167622 | lld:lifeskim |
| pubmed-article:2410524 | lifeskim:mentions | umls-concept:C0033268 | lld:lifeskim |
| pubmed-article:2410524 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:2410524 | lifeskim:mentions | umls-concept:C1710548 | lld:lifeskim |
| pubmed-article:2410524 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:2410524 | pubmed:dateCreated | 1985-9-23 | lld:pubmed |
| pubmed-article:2410524 | pubmed:abstractText | Four monoclonal antibodies to rat apo (apolipoproteins) C were produced. Three of the monoclonals reacted to apoC-I and one to apoC-III. The IgG monoclonals LRB 21 and LRB 45 recognized a spatially close together or identical apoC-I epitope. The monoclonal LRB 80, however, recognized an epitope that is close to, but distinct from, that recognized by LRB 45 and LRB 21. The antibody LRB 45 recognized an apoC-I epitope that is specific for rat apoC-I, and the antibody did not cross-react with dog or human lipoproteins. Rat apoC-I could be detected in all lipoprotein density fractions, but not in the d greater than 1.21 g/ml fraction. Freezing and thawing of serum did not alter the antibody antigen binding. However, lipolysis of whole serum resulted in a 30% increase in antigenic epitope expression. Antibody antigen reaction could be inhibited by subcritical micellar concentration of nonionic detergents. The inhibition was specific but could be partially reversed if lipid-containing serum was used as a dilution buffer. On feeding animals a diet of olive oil and cholesterol for 2 weeks, apoC-I levels decreased. | lld:pubmed |
| pubmed-article:2410524 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2410524 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2410524 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2410524 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2410524 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2410524 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2410524 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2410524 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2410524 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2410524 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2410524 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2410524 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2410524 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2410524 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2410524 | pubmed:month | May | lld:pubmed |
| pubmed-article:2410524 | pubmed:issn | 0022-2275 | lld:pubmed |
| pubmed-article:2410524 | pubmed:author | pubmed-author:RoheimP SPS | lld:pubmed |
| pubmed-article:2410524 | pubmed:author | pubmed-author:WongLL | lld:pubmed |
| pubmed-article:2410524 | pubmed:author | pubmed-author:GallaherW RWR | lld:pubmed |
| pubmed-article:2410524 | pubmed:author | pubmed-author:AndersonP DPD | lld:pubmed |
| pubmed-article:2410524 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2410524 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:2410524 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2410524 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2410524 | pubmed:pagination | 528-39 | lld:pubmed |
| pubmed-article:2410524 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:2410524 | pubmed:meshHeading | pubmed-meshheading:2410524-... | lld:pubmed |
| pubmed-article:2410524 | pubmed:meshHeading | pubmed-meshheading:2410524-... | lld:pubmed |
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| pubmed-article:2410524 | pubmed:meshHeading | pubmed-meshheading:2410524-... | lld:pubmed |
| pubmed-article:2410524 | pubmed:meshHeading | pubmed-meshheading:2410524-... | lld:pubmed |
| pubmed-article:2410524 | pubmed:meshHeading | pubmed-meshheading:2410524-... | lld:pubmed |
| pubmed-article:2410524 | pubmed:meshHeading | pubmed-meshheading:2410524-... | lld:pubmed |
| pubmed-article:2410524 | pubmed:meshHeading | pubmed-meshheading:2410524-... | lld:pubmed |
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| pubmed-article:2410524 | pubmed:meshHeading | pubmed-meshheading:2410524-... | lld:pubmed |
| pubmed-article:2410524 | pubmed:year | 1985 | lld:pubmed |
| pubmed-article:2410524 | pubmed:articleTitle | Monoclonal antibodies to rat C apolipoproteins: production and characterization of a unique antibody whose binding to apoC-I is inhibited by nonionic detergents. | lld:pubmed |
| pubmed-article:2410524 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2410524 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2410524 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
