| pubmed-article:2371290 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2371290 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:2371290 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:2371290 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:2371290 | lifeskim:mentions | umls-concept:C0037868 | lld:lifeskim |
| pubmed-article:2371290 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:2371290 | pubmed:issue | 14 | lld:pubmed |
| pubmed-article:2371290 | pubmed:dateCreated | 1990-8-23 | lld:pubmed |
| pubmed-article:2371290 | pubmed:abstractText | During the process of fertilization in mammals, sperm bind in a relatively species-specific manner to the zona pellucida (ZP) of ovulated eggs. ZP3, a glycoprotein found in the mouse egg zona pellucida, serves as receptor for sperm during gamete adhesion. We report here that a Mr 56,000 protein found on mouse sperm has properties expected for a sperm component that recognizes and binds to ZP3. This sperm protein is radiolabeled preferentially by a photoactivatable heterobifunctional crosslinker ("Denny-Jaffee reagent") covalently linked to purified ZP3, binds very tightly to ZP3-affinity columns, and is localized to heads of acrosome-intact but not acrosome-reacted sperm. These and other findings suggest that this protein may be a "ZP3-binding protein" that, together with the sperm receptor, supports species-specific binding of mouse sperm to unfertilized eggs. | lld:pubmed |
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| pubmed-article:2371290 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2371290 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2371290 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2371290 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2371290 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:2371290 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:2371290 | pubmed:author | pubmed-author:WassarmanP... | lld:pubmed |
| pubmed-article:2371290 | pubmed:author | pubmed-author:BleilJ DJD | lld:pubmed |
| pubmed-article:2371290 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2371290 | pubmed:volume | 87 | lld:pubmed |
| pubmed-article:2371290 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2371290 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2371290 | pubmed:pagination | 5563-7 | lld:pubmed |
| pubmed-article:2371290 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:2371290 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2371290 | pubmed:articleTitle | Identification of a ZP3-binding protein on acrosome-intact mouse sperm by photoaffinity crosslinking. | lld:pubmed |
| pubmed-article:2371290 | pubmed:affiliation | Department of Cell and Developmental Biology, Roche Institute of Molecular Biology, Roche Research Center, Nutley, NJ 07110. | lld:pubmed |
| pubmed-article:2371290 | pubmed:publicationType | Journal Article | lld:pubmed |
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