pubmed-article:2370081 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2370081 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
pubmed-article:2370081 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
pubmed-article:2370081 | lifeskim:mentions | umls-concept:C0009516 | lld:lifeskim |
pubmed-article:2370081 | lifeskim:mentions | umls-concept:C0080194 | lld:lifeskim |
pubmed-article:2370081 | lifeskim:mentions | umls-concept:C1514248 | lld:lifeskim |
pubmed-article:2370081 | lifeskim:mentions | umls-concept:C0205251 | lld:lifeskim |
pubmed-article:2370081 | pubmed:issue | 5-6 | lld:pubmed |
pubmed-article:2370081 | pubmed:dateCreated | 1990-8-23 | lld:pubmed |
pubmed-article:2370081 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2370081 | pubmed:abstractText | The expression of the fourth component of complement (C4) of the mouse can differ 20-fold and is determined by C4-high (C4h) or C4-low (C4l) alleles. To investigate the molecular mechanisms underlying the differences in C4 expression, we compared the transcriptional activity of the C4 genes between high and low C4-producer strains of mice (B10 and FM vs B10.BR) using nuclear transcriptional and chloramphenicol acetyltransferase (CAT) assays. We also compared the level of C4-specific RNA in total and nuclear RNA of the liver. The results revealed no significant difference in transcriptional activity between C4h and C4l genes. However, the steady-state levels of C4 mRNA are ten times lower in C4l strains than in C4h strains, suggesting that the major regulation of C4 plasma levels occurs at the post-transcriptional level. | lld:pubmed |
pubmed-article:2370081 | pubmed:language | eng | lld:pubmed |
pubmed-article:2370081 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2370081 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2370081 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2370081 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2370081 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2370081 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2370081 | pubmed:issn | 0093-7711 | lld:pubmed |
pubmed-article:2370081 | pubmed:author | pubmed-author:KimuraHH | lld:pubmed |
pubmed-article:2370081 | pubmed:author | pubmed-author:NakayamaKK | lld:pubmed |
pubmed-article:2370081 | pubmed:author | pubmed-author:TakahashiMM | lld:pubmed |
pubmed-article:2370081 | pubmed:author | pubmed-author:YokoyamaSS | lld:pubmed |
pubmed-article:2370081 | pubmed:author | pubmed-author:NonakaMM | lld:pubmed |
pubmed-article:2370081 | pubmed:author | pubmed-author:Pattanakitsak... | lld:pubmed |
pubmed-article:2370081 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2370081 | pubmed:volume | 31 | lld:pubmed |
pubmed-article:2370081 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2370081 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2370081 | pubmed:pagination | 361-7 | lld:pubmed |
pubmed-article:2370081 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:2370081 | pubmed:meshHeading | pubmed-meshheading:2370081-... | lld:pubmed |
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pubmed-article:2370081 | pubmed:meshHeading | pubmed-meshheading:2370081-... | lld:pubmed |
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pubmed-article:2370081 | pubmed:meshHeading | pubmed-meshheading:2370081-... | lld:pubmed |
pubmed-article:2370081 | pubmed:meshHeading | pubmed-meshheading:2370081-... | lld:pubmed |
pubmed-article:2370081 | pubmed:year | 1990 | lld:pubmed |
pubmed-article:2370081 | pubmed:articleTitle | Post-transcriptional regulation of complement C4 in low C4-producing strain of mouse. | lld:pubmed |
pubmed-article:2370081 | pubmed:affiliation | Department of Immunobiology, Kanazawa University, Japan. | lld:pubmed |
pubmed-article:2370081 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2370081 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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