| pubmed-article:2251764 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2251764 | lifeskim:mentions | umls-concept:C0007452 | lld:lifeskim |
| pubmed-article:2251764 | lifeskim:mentions | umls-concept:C0021753 | lld:lifeskim |
| pubmed-article:2251764 | lifeskim:mentions | umls-concept:C0027950 | lld:lifeskim |
| pubmed-article:2251764 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:2251764 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:2251764 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:2251764 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:2251764 | lifeskim:mentions | umls-concept:C1515926 | lld:lifeskim |
| pubmed-article:2251764 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:2251764 | pubmed:dateCreated | 1991-1-15 | lld:pubmed |
| pubmed-article:2251764 | pubmed:abstractText | The effects of recombinant bovine interleukin-1 beta (rBIL-1 beta) upon in vitro bovine neutrophil functions were determined. Exposure of peripheral blood neutrophils to various concentrations of rBIL-1 beta induced dose dependent suppression of the phagocyte's ability to migrate under agarose. Preincubation of neutrophils with rBIL-1 beta did not influence their ability to ingest radiolabelled Staphylococcus aureus nor did it induce hydrogen peroxide production or elastase release. However, pretreatment of phagocytes with rBIL-1 beta did result in a dose-dependent enhancement of opsonized zymosan-induced H2O2 production. In contrast, rBIL-1 beta had no effect upon the ability of opsonized zymosan-stimulated neutrophils to release elastase from primary granules. Pretreatment of neutrophils with rBIL-1 beta for as little as 15 min was sufficient to induce suppression of migration and enhancement of opsonized zymosan-induced H2O2 production. These results suggest rBIL-1 beta is capable of directly modulating selected neutrophil activities. In addition, rBIL-1 beta appears to augment the phagocyte's oxidative metabolic responses to subsequent stimulation by microbial antigens. | lld:pubmed |
| pubmed-article:2251764 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2251764 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2251764 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2251764 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2251764 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2251764 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2251764 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2251764 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:2251764 | pubmed:issn | 0165-2427 | lld:pubmed |
| pubmed-article:2251764 | pubmed:author | pubmed-author:BakerP EPE | lld:pubmed |
| pubmed-article:2251764 | pubmed:author | pubmed-author:CanningP CPC | lld:pubmed |
| pubmed-article:2251764 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2251764 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:2251764 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2251764 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2251764 | pubmed:pagination | 1-12 | lld:pubmed |
| pubmed-article:2251764 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2251764 | pubmed:meshHeading | pubmed-meshheading:2251764-... | lld:pubmed |
| pubmed-article:2251764 | pubmed:meshHeading | pubmed-meshheading:2251764-... | lld:pubmed |
| pubmed-article:2251764 | pubmed:meshHeading | pubmed-meshheading:2251764-... | lld:pubmed |
| pubmed-article:2251764 | pubmed:meshHeading | pubmed-meshheading:2251764-... | lld:pubmed |
| pubmed-article:2251764 | pubmed:meshHeading | pubmed-meshheading:2251764-... | lld:pubmed |
| pubmed-article:2251764 | pubmed:meshHeading | pubmed-meshheading:2251764-... | lld:pubmed |
| pubmed-article:2251764 | pubmed:meshHeading | pubmed-meshheading:2251764-... | lld:pubmed |
| pubmed-article:2251764 | pubmed:meshHeading | pubmed-meshheading:2251764-... | lld:pubmed |
| pubmed-article:2251764 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2251764 | pubmed:articleTitle | Selective alteration of bovine neutrophil responses by recombinant bovine interleukin-1 beta. | lld:pubmed |
| pubmed-article:2251764 | pubmed:affiliation | National Animal Disease Center, U.S.D.A., Ames, IA 50010. | lld:pubmed |
| pubmed-article:2251764 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2251764 | pubmed:publicationType | In Vitro | lld:pubmed |
