| pubmed-article:2179053 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2179053 | lifeskim:mentions | umls-concept:C0036025 | lld:lifeskim |
| pubmed-article:2179053 | lifeskim:mentions | umls-concept:C1158501 | lld:lifeskim |
| pubmed-article:2179053 | lifeskim:mentions | umls-concept:C1705914 | lld:lifeskim |
| pubmed-article:2179053 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:2179053 | pubmed:dateCreated | 1990-4-16 | lld:pubmed |
| pubmed-article:2179053 | pubmed:abstractText | Y's are a dispersed family of repeats that vary in copy number, location and restriction fragment lengths between strains but exhibit within-strain homogeneity. We have studied mitotic recombination between members of the subtelomeric Y' repeated sequence family of Saccharomyces cerevisiae. Individual copies of Y's were marked with SUP11 and URA3 which allowed for the selection of duplications and losses of the marked Y's. Duplications occurred by ectopic recombinational interactions between Y's at different chromosome ends as well as by unequal sister chromatid exchange. Several of the ectopic duplications resulted in an originally Y'-less chromosome end acquiring a marked Y'. Among losses, most resulted from ectopic exchange or conversion in which only the marker sequence was lost. In some losses, the chromosome end became Y'-less. Although the two subsets of Y's, Y'-longs (6.7 kb) and Y'-shorts (5.2 kb), share extensive sequence homology, a marked Y' recombines highly preferentially within its own subset. These mitotic interactions can in part explain the maintenance of Y's and their subsets, the homogeneity among Y's within a strain, as well as diversity between strains. | lld:pubmed |
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| pubmed-article:2179053 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:2179053 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2179053 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2179053 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:2179053 | pubmed:issn | 0016-6731 | lld:pubmed |
| pubmed-article:2179053 | pubmed:author | pubmed-author:HaberJ EJE | lld:pubmed |
| pubmed-article:2179053 | pubmed:author | pubmed-author:LouisE JEJ | lld:pubmed |
| pubmed-article:2179053 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2179053 | pubmed:volume | 124 | lld:pubmed |
| pubmed-article:2179053 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2179053 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2179053 | pubmed:pagination | 547-59 | lld:pubmed |
| pubmed-article:2179053 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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| pubmed-article:2179053 | pubmed:meshHeading | pubmed-meshheading:2179053-... | lld:pubmed |
| pubmed-article:2179053 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2179053 | pubmed:articleTitle | Mitotic recombination among subtelomeric Y' repeats in Saccharomyces cerevisiae. | lld:pubmed |
| pubmed-article:2179053 | pubmed:affiliation | Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts 02254. | lld:pubmed |
| pubmed-article:2179053 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2179053 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:2179053 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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