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pubmed-article:21693247pubmed:dateCreated2011-6-22lld:pubmed
pubmed-article:21693247pubmed:abstractTextThe Banff criteria (from 2005 to 2009) use "T cell-mediated rejection" to indicate acute cellular rejection. Vasculitis in smaller arteries is an important diagnostic criterion for moderate and severe T cell-mediated rejection. The renal allograft endothelium is a significant target of inflammatory response-mediated tissue damage. Medium-size arteries (arcuate arteries) are mostly absent in routine allograft biopsies, so identification of vasculitis relies on its identification in small arteries (arterioles to interlobar arteries). Although inflammation in terminal vessels such as the glomerular capillaries has been previously recognized, their role in grading the rejection process is not well characterized. We therefore evaluated the expression of CD3-positive T lymphocytes and CD68-positive macrophages in glomeruli, small arteries, and arcuate arteries of nephrectomy specimens obtained from transplant and renal tumor patients.lld:pubmed
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pubmed-article:21693247pubmed:authorpubmed-author:DumlerFFlld:pubmed
pubmed-article:21693247pubmed:authorpubmed-author:ZhangP LPLlld:pubmed
pubmed-article:21693247pubmed:authorpubmed-author:RocherL LLLlld:pubmed
pubmed-article:21693247pubmed:authorpubmed-author:CohnS RSRlld:pubmed
pubmed-article:21693247pubmed:authorpubmed-author:RooneyM TMTlld:pubmed
pubmed-article:21693247pubmed:authorpubmed-author:DesaiH SHSlld:pubmed
pubmed-article:21693247pubmed:authorpubmed-author:ReddyG HGHlld:pubmed
pubmed-article:21693247pubmed:authorpubmed-author:ParasuramanR...lld:pubmed
pubmed-article:21693247pubmed:authorpubmed-author:Samarpungavan...lld:pubmed
pubmed-article:21693247pubmed:copyrightInfoCopyright © 2011 Elsevier Inc. All rights reserved.lld:pubmed
pubmed-article:21693247pubmed:issnTypeElectroniclld:pubmed
pubmed-article:21693247pubmed:volume43lld:pubmed
pubmed-article:21693247pubmed:ownerNLMlld:pubmed
pubmed-article:21693247pubmed:authorsCompleteYlld:pubmed
pubmed-article:21693247pubmed:pagination1629-33lld:pubmed
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pubmed-article:21693247pubmed:year2011lld:pubmed
pubmed-article:21693247pubmed:articleTitleGlomerulitis during acute cellular rejection may be a surrogate marker of vasculitis in renal allografts--better index for diagnosis of vasculitis.lld:pubmed
pubmed-article:21693247pubmed:affiliationDepartment of Anatomic Pathology, William Beaumont Hospital, Royal Oak, Michigan, USA.lld:pubmed
pubmed-article:21693247pubmed:publicationTypeJournal Articlelld:pubmed