| pubmed-article:21670331 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21670331 | lifeskim:mentions | umls-concept:C0278329 | lld:lifeskim |
| pubmed-article:21670331 | pubmed:issue | 16 | lld:pubmed |
| pubmed-article:21670331 | pubmed:dateCreated | 2011-9-13 | lld:pubmed |
| pubmed-article:21670331 | pubmed:abstractText | Judicious prescribing is a prerequisite for safe and appropriate medication use. Based on evidence and lessons from recent studies demonstrating problems with widely prescribed medications, we offer a series of principles as a prescription for more cautious and conservative prescribing. These principles urge clinicians to (1) think beyond drugs (consider nondrug therapy, treatable underlying causes, and prevention); (2) practice more strategic prescribing (defer nonurgent drug treatment; avoid unwarranted drug switching; be circumspect about unproven drug uses; and start treatment with only 1 new drug at a time); (3) maintain heightened vigilance regarding adverse effects (suspect drug reactions; be aware of withdrawal syndromes; and educate patients to anticipate reactions); (4) exercise caution and skepticism regarding new drugs (seek out unbiased information; wait until drugs have sufficient time on the market; be skeptical about surrogate rather than true clinical outcomes; avoid stretching indications; avoid seduction by elegant molecular pharmacology; beware of selective drug trial reporting); (5) work with patients for a shared agenda (do not automatically accede to drug requests; consider nonadherence before adding drugs to regimen; avoid restarting previously unsuccessful drug treatment; discontinue treatment with unneeded medications; and respect patients' reservations about drugs); and (6) consider long-term, broader impacts (weigh long-term outcomes, and recognize that improved systems may outweigh marginal benefits of new drugs). | lld:pubmed |
| pubmed-article:21670331 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21670331 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21670331 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21670331 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:21670331 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21670331 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:21670331 | pubmed:issn | 1538-3679 | lld:pubmed |
| pubmed-article:21670331 | pubmed:author | pubmed-author:DupreD ADA | lld:pubmed |
| pubmed-article:21670331 | pubmed:author | pubmed-author:SchiffGordon... | lld:pubmed |
| pubmed-article:21670331 | pubmed:author | pubmed-author:GalanterWilli... | lld:pubmed |
| pubmed-article:21670331 | pubmed:author | pubmed-author:LambertBruce... | lld:pubmed |
| pubmed-article:21670331 | pubmed:author | pubmed-author:LodolceAmy... | lld:pubmed |
| pubmed-article:21670331 | pubmed:author | pubmed-author:KoronkowskiMi... | lld:pubmed |
| pubmed-article:21670331 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21670331 | pubmed:day | 12 | lld:pubmed |
| pubmed-article:21670331 | pubmed:volume | 171 | lld:pubmed |
| pubmed-article:21670331 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21670331 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21670331 | pubmed:pagination | 1433-40 | lld:pubmed |
| pubmed-article:21670331 | pubmed:meshHeading | pubmed-meshheading:21670331... | lld:pubmed |
| pubmed-article:21670331 | pubmed:meshHeading | pubmed-meshheading:21670331... | lld:pubmed |
| pubmed-article:21670331 | pubmed:meshHeading | pubmed-meshheading:21670331... | lld:pubmed |
| pubmed-article:21670331 | pubmed:meshHeading | pubmed-meshheading:21670331... | lld:pubmed |
| pubmed-article:21670331 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21670331 | pubmed:articleTitle | Principles of conservative prescribing. | lld:pubmed |
| pubmed-article:21670331 | pubmed:affiliation | Center for Patient Safety Research and Practice, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA. gschiff@partners.org | lld:pubmed |
| pubmed-article:21670331 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21670331 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:21670331 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:21670331 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
