| pubmed-article:21636698 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21636698 | lifeskim:mentions | umls-concept:C0302908 | lld:lifeskim |
| pubmed-article:21636698 | lifeskim:mentions | umls-concept:C1285572 | lld:lifeskim |
| pubmed-article:21636698 | lifeskim:mentions | umls-concept:C0037813 | lld:lifeskim |
| pubmed-article:21636698 | lifeskim:mentions | umls-concept:C1314763 | lld:lifeskim |
| pubmed-article:21636698 | lifeskim:mentions | umls-concept:C0521115 | lld:lifeskim |
| pubmed-article:21636698 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:21636698 | pubmed:dateCreated | 2011-7-29 | lld:pubmed |
| pubmed-article:21636698 | pubmed:abstractText | ?-1-Antitrypsin (A1AT) deficiency results from a genetic disorder at 2 common loci. Diagnosis requires quantification of A1AT and subsequent identification of the specific variant. The current algorithm of laboratory testing for the diagnosis of A1AT deficiency uses a combination of quantification (nephelometry), genotyping, and/or phenotyping. We developed a multiple reaction monitoring liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for simultaneous quantification of A1AT and identification of the 2 most common deficiency alleles present in 95% of the patients with A1AT deficiency. | lld:pubmed |
| pubmed-article:21636698 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21636698 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21636698 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21636698 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21636698 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21636698 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21636698 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21636698 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:21636698 | pubmed:issn | 1530-8561 | lld:pubmed |
| pubmed-article:21636698 | pubmed:author | pubmed-author:ZhuYiY | lld:pubmed |
| pubmed-article:21636698 | pubmed:author | pubmed-author:BensonLinda... | lld:pubmed |
| pubmed-article:21636698 | pubmed:author | pubmed-author:KatzmannJerry... | lld:pubmed |
| pubmed-article:21636698 | pubmed:author | pubmed-author:SnyderMelissa... | lld:pubmed |
| pubmed-article:21636698 | pubmed:author | pubmed-author:ChenYuhongY | lld:pubmed |
| pubmed-article:21636698 | pubmed:author | pubmed-author:BergenH... | lld:pubmed |
| pubmed-article:21636698 | pubmed:author | pubmed-author:TostrudLinda... | lld:pubmed |
| pubmed-article:21636698 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21636698 | pubmed:volume | 57 | lld:pubmed |
| pubmed-article:21636698 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21636698 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21636698 | pubmed:pagination | 1161-8 | lld:pubmed |
| pubmed-article:21636698 | pubmed:meshHeading | pubmed-meshheading:21636698... | lld:pubmed |
| pubmed-article:21636698 | pubmed:meshHeading | pubmed-meshheading:21636698... | lld:pubmed |
| pubmed-article:21636698 | pubmed:meshHeading | pubmed-meshheading:21636698... | lld:pubmed |
| pubmed-article:21636698 | pubmed:meshHeading | pubmed-meshheading:21636698... | lld:pubmed |
| pubmed-article:21636698 | pubmed:meshHeading | pubmed-meshheading:21636698... | lld:pubmed |
| pubmed-article:21636698 | pubmed:meshHeading | pubmed-meshheading:21636698... | lld:pubmed |
| pubmed-article:21636698 | pubmed:meshHeading | pubmed-meshheading:21636698... | lld:pubmed |
| pubmed-article:21636698 | pubmed:meshHeading | pubmed-meshheading:21636698... | lld:pubmed |
| pubmed-article:21636698 | pubmed:meshHeading | pubmed-meshheading:21636698... | lld:pubmed |
| pubmed-article:21636698 | pubmed:meshHeading | pubmed-meshheading:21636698... | lld:pubmed |
| pubmed-article:21636698 | pubmed:meshHeading | pubmed-meshheading:21636698... | lld:pubmed |
| pubmed-article:21636698 | pubmed:meshHeading | pubmed-meshheading:21636698... | lld:pubmed |
| pubmed-article:21636698 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21636698 | pubmed:articleTitle | Simultaneous phenotyping and quantification of ?-1-antitrypsin by liquid chromatography-tandem mass spectrometry. | lld:pubmed |
| pubmed-article:21636698 | pubmed:affiliation | Division of Clinical Pharmacology, Department of Molecular and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA. | lld:pubmed |
| pubmed-article:21636698 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21636698 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:21636698 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:21636698 | lld:pubmed |
