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pubmed-article:21456071pubmed:abstractTextRecent data has shown that prostate cancer (PCA) cells are capable of producing testosterone directly from cholesterol, which may contribute to the development of castration resistance. While up-regulation of steroidogenic enzymes has been previously described during castration-resistant prostate cancer (CRPC) progression, regulation of this process is poorly defined. These data examine the role of luteinizing hormone (LH) in the regulation of steroidogenic machinery in PCA cells.lld:pubmed
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pubmed-article:21456071pubmed:authorpubmed-author:LiuStephen...lld:pubmed
pubmed-article:21456071pubmed:copyrightInfoCopyright © 2010 Wiley-Liss, Inc.lld:pubmed
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pubmed-article:21456071pubmed:articleTitleEffect of luteinizing hormone on the steroidogenic pathway in prostate cancer.lld:pubmed
pubmed-article:21456071pubmed:affiliationUniversity of Southern California/Norris Comprehensive Cancer Center, Keck School of Medicine, Los Angeles, CA 90033, USA. pinski_j@ccnt.usc.edulld:pubmed
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