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pubmed-article:21410164pubmed:abstractTextPinnarine (1), a new macrocyclic alkaloid, was isolated from the black marine sponge Halichondria okadai. The structure was elucidated on the basis of 2D NMR and comparison with the spectra of the co-isolated known halichlorine. Further confirmation of the structure and the absolute configuration was validated by a synthetic method from authentic pinnaic acid and CD analysis. The isolation of pinnarine also suggested a biogenetic pathway from pinnaic acid to halichlorine.lld:pubmed
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pubmed-article:21410164pubmed:year2011lld:pubmed
pubmed-article:21410164pubmed:articleTitlePinnarine, another member of the halichlorine family. Isolation and preparation from pinnaic acid.lld:pubmed
pubmed-article:21410164pubmed:affiliationDepartment of Chemistry, Graduate School of Science, Nagoya University, Furo-cho, Chikusa, Nagoya 464-8602, Japan.lld:pubmed
pubmed-article:21410164pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:21410164pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed