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pubmed-article:21393095pubmed:abstractTextSturge-Weber syndrome is a neurocutaneous disorder classically characterized by the presence of facial port-wine stain and ipsilateral leptomeningeal angiomatosis. It is often associated with refractory epilepsy which requires surgical treatment. We present a case of a patient who initially presented with partial seizures of temporo-occipital origin, ipsilateral to the pial angiomatosis. During the course of the disease, the patient developed medically refractory epilepsy with partial seizures originating predominantly from the contralateral temporo-occipital area as well as myoclonic and myoclonic-astatic seizures. Resection of the occipital and temporal lobe affected by the pial angioma resulted in favourable outcome. Bilateral dysfunction observed in Sturge-Weber syndrome may result in an increased capability of focal discharges to generate synchronous epileptiform activity leading to an increased incidence of generalised seizures, most probably via a mechanism of secondary bilateral synchrony. [Published with video sequences].lld:pubmed
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pubmed-article:21393095pubmed:authorpubmed-author:JefferysJohn...lld:pubmed
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pubmed-article:21393095pubmed:authorpubmed-author:JiruskaPremys...lld:pubmed
pubmed-article:21393095pubmed:authorpubmed-author:KomarekVladim...lld:pubmed
pubmed-article:21393095pubmed:authorpubmed-author:CmejlaRomanRlld:pubmed
pubmed-article:21393095pubmed:authorpubmed-author:SebronovaVera...lld:pubmed
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pubmed-article:21393095pubmed:year2011lld:pubmed
pubmed-article:21393095pubmed:articleTitleSturge-Weber syndrome: a favourable surgical outcome in a case with contralateral seizure onset and myoclonic-astatic seizures.lld:pubmed
pubmed-article:21393095pubmed:affiliationNeuronal Networks Group, Neuropharmacology and Neurobiology, School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, United Kingdom.lld:pubmed
pubmed-article:21393095pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:21393095pubmed:publicationTypeCase Reportslld:pubmed
pubmed-article:21393095pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed