| pubmed-article:21272404 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21272404 | lifeskim:mentions | umls-concept:C0013264 | lld:lifeskim |
| pubmed-article:21272404 | lifeskim:mentions | umls-concept:C0043100 | lld:lifeskim |
| pubmed-article:21272404 | lifeskim:mentions | umls-concept:C0449438 | lld:lifeskim |
| pubmed-article:21272404 | lifeskim:mentions | umls-concept:C0015219 | lld:lifeskim |
| pubmed-article:21272404 | lifeskim:mentions | umls-concept:C1704775 | lld:lifeskim |
| pubmed-article:21272404 | lifeskim:mentions | umls-concept:C0205296 | lld:lifeskim |
| pubmed-article:21272404 | lifeskim:mentions | umls-concept:C1514923 | lld:lifeskim |
| pubmed-article:21272404 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:21272404 | pubmed:dateCreated | 2011-5-5 | lld:pubmed |
| pubmed-article:21272404 | pubmed:abstractText | The life expectancy of patients with Duchenne muscular dystrophy (DMD) has increased. A cross-sectional study of DMD patients showed that 54 % of 13-year-old patients are obese and that 54 % of 18-year-old patients are underweight. We aimed to describe the natural evolution of weight status in DMD. This retrospective multi-centre audit collected body-weight measurements for seventy DMD patients born before 1992. The body-weight:age ratio (W:A) was used to evaluate weight status in reference to the Griffiths and Edwards chart. At the age of 13 years, 73 % were obese and 4 % were underweight. At maximal follow-up (age 15-26 years, mean 18·3 (sd 2·3) years), 47 % were obese and 34 % were underweight. Obesity at the age of 13 years was associated with later obesity, whereas normal weight status and underweight in 13-year-old patients predicted later underweight. A W:A ? 151 % in 13-year-old patients predicted later obesity, and a W:A ? 126·5 % predicted later underweight. Our audit provides the first longitudinal information about the spontaneous outcome of weight status in DMD. Patients (13 years old) with a W:A ? 151 % were more likely to become obese in late adolescence, but obesity prevented later underweight. These data suggest that mild obesity in 13-year-old DMD patients (W:A between 120 and 150 %) should not be discouraged because it prevents later underweight. | lld:pubmed |
| pubmed-article:21272404 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21272404 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21272404 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21272404 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21272404 | pubmed:month | May | lld:pubmed |
| pubmed-article:21272404 | pubmed:issn | 1475-2662 | lld:pubmed |
| pubmed-article:21272404 | pubmed:author | pubmed-author:CarpentierAla... | lld:pubmed |
| pubmed-article:21272404 | pubmed:author | pubmed-author:GottrandFrédé... | lld:pubmed |
| pubmed-article:21272404 | pubmed:author | pubmed-author:GuimberDomini... | lld:pubmed |
| pubmed-article:21272404 | pubmed:author | pubmed-author:CuissetJean-M... | lld:pubmed |
| pubmed-article:21272404 | pubmed:author | pubmed-author:TiffreauVince... | lld:pubmed |
| pubmed-article:21272404 | pubmed:author | pubmed-author:NeveVéronique... | lld:pubmed |
| pubmed-article:21272404 | pubmed:author | pubmed-author:MayerMichèleM | lld:pubmed |
| pubmed-article:21272404 | pubmed:author | pubmed-author:MartigneLéoni... | lld:pubmed |
| pubmed-article:21272404 | pubmed:author | pubmed-author:SalleronJulia... | lld:pubmed |
| pubmed-article:21272404 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21272404 | pubmed:volume | 105 | lld:pubmed |
| pubmed-article:21272404 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21272404 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21272404 | pubmed:pagination | 1486-91 | lld:pubmed |
| pubmed-article:21272404 | pubmed:meshHeading | pubmed-meshheading:21272404... | lld:pubmed |
| pubmed-article:21272404 | pubmed:meshHeading | pubmed-meshheading:21272404... | lld:pubmed |
| pubmed-article:21272404 | pubmed:meshHeading | pubmed-meshheading:21272404... | lld:pubmed |
| pubmed-article:21272404 | pubmed:meshHeading | pubmed-meshheading:21272404... | lld:pubmed |
| pubmed-article:21272404 | pubmed:meshHeading | pubmed-meshheading:21272404... | lld:pubmed |
| pubmed-article:21272404 | pubmed:meshHeading | pubmed-meshheading:21272404... | lld:pubmed |
| pubmed-article:21272404 | pubmed:meshHeading | pubmed-meshheading:21272404... | lld:pubmed |
| pubmed-article:21272404 | pubmed:meshHeading | pubmed-meshheading:21272404... | lld:pubmed |
| pubmed-article:21272404 | pubmed:meshHeading | pubmed-meshheading:21272404... | lld:pubmed |
| pubmed-article:21272404 | pubmed:meshHeading | pubmed-meshheading:21272404... | lld:pubmed |
| pubmed-article:21272404 | pubmed:meshHeading | pubmed-meshheading:21272404... | lld:pubmed |
| pubmed-article:21272404 | pubmed:meshHeading | pubmed-meshheading:21272404... | lld:pubmed |
| pubmed-article:21272404 | pubmed:meshHeading | pubmed-meshheading:21272404... | lld:pubmed |
| pubmed-article:21272404 | pubmed:meshHeading | pubmed-meshheading:21272404... | lld:pubmed |
| pubmed-article:21272404 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21272404 | pubmed:articleTitle | Natural evolution of weight status in Duchenne muscular dystrophy: a retrospective audit. | lld:pubmed |
| pubmed-article:21272404 | pubmed:affiliation | Service de Gastroentérologie, Hépatologie et Nutrition Pédiatrique, Hôpital Jeanne de Flandre, Centre Hospitalier Régional et Universitaire, Lille, France. leonie.martigne@chru-lille.fr | lld:pubmed |
| pubmed-article:21272404 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21272404 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:21272404 | pubmed:publicationType | Multicenter Study | lld:pubmed |
