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pubmed-article:21212665pubmed:abstractTextBrain arteriovenous malformations (BAVM) are high-flow vascular lesions prone to intracranial hemorrhage (ICH). Abnormal angiogenesis is a key characteristic of BAVM tissue. Angiopoietin-like 4 (ANGPTL4), a secreted glycoprotein, is thought to be involved in angiogenesis and required for proper postnatal blood vessel partitioning. We investigated whether common single nucleotide polymorphisms (SNPs) in ANGPTL4 were associated with risk of BAVM or ICH.lld:pubmed
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pubmed-article:21212665pubmed:copyrightInfoCopyright © 2011 S. Karger AG, Basel.lld:pubmed
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pubmed-article:21212665pubmed:articleTitleAngiopoietin-like 4 (ANGPTL4) gene polymorphisms and risk of brain arteriovenous malformations.lld:pubmed
pubmed-article:21212665pubmed:affiliationCenter for Cerebrovascular Research, Department of Anesthesia and Perioperative Care, University of California, San Francisco, 94110, USA.lld:pubmed
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pubmed-article:21212665pubmed:publicationTypeResearch Support, N.I.H., Extramurallld:pubmed
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