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pubmed-article:21147821pubmed:abstractTextRecent studies have suggested that biopsy of several trophectoderm (TE) cells from blastocysts followed by comparative genomic hybridization (CGH) analysis might represent an optimal strategy for aneuploidy detection, but few data on accuracy are available. The main question concerns the rate of mosaicism at the blastocyst stage, and to what extent this might cause misdiagnoses. We assessed blastocyst aneuploidy and mosaicism rates and evaluated the accuracy and efficiency of CGH and microarray-CGH (aCGH) for TE analysis.lld:pubmed
pubmed-article:21147821pubmed:languageenglld:pubmed
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pubmed-article:21147821pubmed:authorpubmed-author:GordonAnthony...lld:pubmed
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pubmed-article:21147821pubmed:year2011lld:pubmed
pubmed-article:21147821pubmed:articleTitleCytogenetic analysis of human blastocysts with the use of FISH, CGH and aCGH: scientific data and technical evaluation.lld:pubmed
pubmed-article:21147821pubmed:affiliationNuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford OX3 9DU, UK. elpida.fragouli@obs-gyn.ox.ac.uklld:pubmed
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pubmed-article:21147821pubmed:publicationTypeEvaluation Studieslld:pubmed