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pubmed-article:21143894pubmed:abstractTextSaikosaponin-a and -d, two naturally occurring compounds derived from Bupleurum radix, have been shown to exert anti-cancer activity in several cancer cell lines. However, the effect of combination of saikosaponins with chemotherapeutic drugs has never been addressed. Thus, we investigated whether these two saikosaponins have chemosensitization effect on cisplatin-induced cancer cell cytotoxicity.lld:pubmed
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pubmed-article:21143894pubmed:authorpubmed-author:HarhJ YJYlld:pubmed
pubmed-article:21143894pubmed:authorpubmed-author:LiH KHKlld:pubmed
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pubmed-article:21143894pubmed:authorpubmed-author:WangXiaXlld:pubmed
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pubmed-article:21143894pubmed:articleTitleReactive oxygen species-mediated apoptosis contributes to chemosensitization effect of saikosaponins on cisplatin-induced cytotoxicity in cancer cells.lld:pubmed
pubmed-article:21143894pubmed:affiliationLaboratory of Molecular and Translational Medicine, West China Institute of Women and Children's Health, West China Second University Hospital, Sichuan University, Chengdu 610041, PR China.lld:pubmed
pubmed-article:21143894pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:21143894pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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