| pubmed-article:21071867 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21071867 | lifeskim:mentions | umls-concept:C0003402 | lld:lifeskim |
| pubmed-article:21071867 | lifeskim:mentions | umls-concept:C0029431 | lld:lifeskim |
| pubmed-article:21071867 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
| pubmed-article:21071867 | lifeskim:mentions | umls-concept:C0521447 | lld:lifeskim |
| pubmed-article:21071867 | lifeskim:mentions | umls-concept:C0018026 | lld:lifeskim |
| pubmed-article:21071867 | lifeskim:mentions | umls-concept:C1367028 | lld:lifeskim |
| pubmed-article:21071867 | lifeskim:mentions | umls-concept:C0023688 | lld:lifeskim |
| pubmed-article:21071867 | lifeskim:mentions | umls-concept:C1450054 | lld:lifeskim |
| pubmed-article:21071867 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:21071867 | lifeskim:mentions | umls-concept:C1522492 | lld:lifeskim |
| pubmed-article:21071867 | lifeskim:mentions | umls-concept:C0682002 | lld:lifeskim |
| pubmed-article:21071867 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:21071867 | pubmed:dateCreated | 2010-11-30 | lld:pubmed |
| pubmed-article:21071867 | pubmed:abstractText | Gold nanoparticles inhibited osteoclast (OC) formation induced by the receptor activator of nuclear factor-?B ligand (RANKL) in bone marrow-derived macrophages (BMMs). This was accompanied by a decreased level of tartrate-resistant alkaline phosphatase (TRAP) and less activation of nuclear factor (NF)-?B. The nanoparticles also reduced the production of reactive oxygen species (ROS) in response to RANKL and upregulated RANKL-induced glutathione peroxidase-1 (Gpx-1), suggesting a role as an antioxidant in the BMM. The inhibitory effects on OC formation might have been due to elevated defense against oxidative stress. | lld:pubmed |
| pubmed-article:21071867 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21071867 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21071867 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21071867 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21071867 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21071867 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21071867 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21071867 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21071867 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21071867 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21071867 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21071867 | pubmed:issn | 1347-6947 | lld:pubmed |
| pubmed-article:21071867 | pubmed:author | pubmed-author:ChoiHye-SeonH... | lld:pubmed |
| pubmed-article:21071867 | pubmed:author | pubmed-author:KimHye-JinHJ | lld:pubmed |
| pubmed-article:21071867 | pubmed:author | pubmed-author:KimSong-HeeSH | lld:pubmed |
| pubmed-article:21071867 | pubmed:author | pubmed-author:KyungTae-Wook... | lld:pubmed |
| pubmed-article:21071867 | pubmed:author | pubmed-author:KimJi-SoonJS | lld:pubmed |
| pubmed-article:21071867 | pubmed:author | pubmed-author:KimYoun-Young... | lld:pubmed |
| pubmed-article:21071867 | pubmed:author | pubmed-author:SulOk-JooOJ | lld:pubmed |
| pubmed-article:21071867 | pubmed:author | pubmed-author:KimJin-ChunJC | lld:pubmed |
| pubmed-article:21071867 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21071867 | pubmed:volume | 74 | lld:pubmed |
| pubmed-article:21071867 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21071867 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21071867 | pubmed:pagination | 2209-13 | lld:pubmed |
| pubmed-article:21071867 | pubmed:dateRevised | 2011-8-11 | lld:pubmed |
| pubmed-article:21071867 | pubmed:meshHeading | pubmed-meshheading:21071867... | lld:pubmed |
| pubmed-article:21071867 | pubmed:meshHeading | pubmed-meshheading:21071867... | lld:pubmed |
| pubmed-article:21071867 | pubmed:meshHeading | pubmed-meshheading:21071867... | lld:pubmed |
| pubmed-article:21071867 | pubmed:meshHeading | pubmed-meshheading:21071867... | lld:pubmed |
| pubmed-article:21071867 | pubmed:meshHeading | pubmed-meshheading:21071867... | lld:pubmed |
| pubmed-article:21071867 | pubmed:meshHeading | pubmed-meshheading:21071867... | lld:pubmed |
| pubmed-article:21071867 | pubmed:meshHeading | pubmed-meshheading:21071867... | lld:pubmed |
| pubmed-article:21071867 | pubmed:meshHeading | pubmed-meshheading:21071867... | lld:pubmed |
| pubmed-article:21071867 | pubmed:meshHeading | pubmed-meshheading:21071867... | lld:pubmed |
| pubmed-article:21071867 | pubmed:meshHeading | pubmed-meshheading:21071867... | lld:pubmed |
| pubmed-article:21071867 | pubmed:meshHeading | pubmed-meshheading:21071867... | lld:pubmed |
| pubmed-article:21071867 | pubmed:meshHeading | pubmed-meshheading:21071867... | lld:pubmed |
| pubmed-article:21071867 | pubmed:meshHeading | pubmed-meshheading:21071867... | lld:pubmed |
| pubmed-article:21071867 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:21071867 | pubmed:articleTitle | Gold nanoparticles inhibited the receptor activator of nuclear factor-?b ligand (RANKL)-induced osteoclast formation by acting as an antioxidant. | lld:pubmed |
| pubmed-article:21071867 | pubmed:affiliation | Department of Biological Sciences (BK21 Program) and Immunomodulation Research Center, University of Ulsan, Korea. | lld:pubmed |
| pubmed-article:21071867 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21071867 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
